认识I型干扰素病  

Elucidation on type Ⅰ interferonopathies

作　　者：于仲勋 宋红梅[1] Yu Zhongxun;Song Hongmei(Department of Pediatrics,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]中国医学科学院北京协和医院儿科,北京100730

出　　处：《中华实用儿科临床杂志》2022年第1期2-5,共4页Chinese Journal of Applied Clinical Pediatrics

摘　　要：Ⅰ型干扰素病是近10年来概念较新的一组疾病,隶属于免疫缺陷病中的自身炎症性疾病,其发病率低,临床表现多样,临床不易识别,且诊断较为困难。现以较短篇幅对该类疾病的概念、发病机制、诊断和治疗做一介绍,以期增加临床医师对其的认识,从而达到早识别、早检测、早明确、早干预的目标,造福于更多此类患者及其家庭。TypeⅠinterferonopathies is a relatively new group of diseases in the last decade,which belong to auto-inflammatory disorders characterized by robust inflammation.Its low incidence and diverse clinical manifestations make it difficult for the clinical identification and diagnosis of this disease.In this article,the concept,pathogenesis,diagnosis and treatment options of this disease was introduced briefly,in order to enhance clinicians′knowledge of them,thus achieving the goal of early recognition,early detection,early identification and early intervention for the benefit of more patients and their families.

关 键 词：自身炎症性疾病 Ⅰ型干扰素病 JAK抑制剂 

分 类 号：R593.3[医药卫生—内科学]