某些特殊病原体在慢性前列腺炎/慢性骨盆疼痛综合征中的可能作用  

Possible roles of certain special pathogens in male chronic prostatitis/chronic pelvic pain syndrome

作　　者：李豫 商学军 LI Yu;SHANG Xue-jun(Department of Andrology,Nanjing School of Clinical Medicine,Southern Medical University/General Hospital of Eastern Theater Command,Nanjing,Jiangsu 210002,China)

机构地区：[1]南方医科大学南京临床医学院/东部战区总医院男科,江苏南京210002

出　　处：《中华男科学杂志》2022年第2期162-166,共5页National Journal of Andrology

基　　金：国家自然科学基金(81771646);军队计生专项研究任务计划(17JS013)。

摘　　要：慢性前列腺炎/慢性骨盆疼痛综合征(CP/CPSS)发病机制尚不明,其中病原体感染可能是主要原因之一。除大肠埃希菌、金黄色葡萄球菌等典型病原体之外,还有许多特殊病原体,因其难以被常规方法鉴定分离,临床上极易被忽视。本综述对潜在的病原体在CP/CPPS中的可能作用作一概述,以期引起临床医生的重视,帮助解决临床难题。对于临床部分以慢性炎症为主,反复发作或加重的“无菌性”前列腺炎患者,特别是经长期广谱抗生素治疗者,提示这可能是由于特殊病原体造成的前列腺感染,提醒临床医生注意排查,予以更多关注。The etiology and pathogenesis of chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)have not been fully understood so far.It is indicated that pathogen infection may play a significant role in the development of this disease.In addition to typical pathogens such as Escherichia coli and Staphylococcus aureus,many special pathogens are difficult to be identified and isolated by conventional methods and are easily ignored in clinical practice.This review summarizes the possible roles of potential pathogens in CP/CPPS,in order to arouse the attention of clinicians and help solve related clinical problems.Clinicians are advised to attend better to the screening and study of abacterial prostatitis with dominant clinical characteristics of chronic inflammation,recurrence or aggravation,especially the cases receiving long-term broad-spectrum antibiotics,suggesting prostatic infection caused by special pathogens.

关 键 词：慢性前列腺炎/慢性骨盆疼痛综合征 病原体 微生物组 泌尿生殖系统感染 

分 类 号：R697.33[医药卫生—泌尿科学] R375[医药卫生—外科学]