miR-210对缺血性心脑血管疾病研究概述  

Research Overview of MicroRNA-210 in Ischemic Cardiovascular and Cerebrovascular Diseases

作　　者：孙诗杰 祝美珍[1] 韦亮 苏萍 何宏盾 SUN Shijie;ZHU Meizhen;WEI Liang;SU Ping;HE Hongdun(Guangxi University of Traditional Chinese Medicine,Nanning 530001,Guangxi,China)

机构地区：[1]广西中医药大学,广西南宁530001

出　　处：《辽宁中医药大学学报》2022年第1期160-164,共5页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金地区基金项目(81460725);广西一流学科建设开放课题(0502001855,KJT1900406)。

摘　　要：缺血性心脑血管疾病在世界范围内的患病率及病死率不断增加,越来越多研究表明,基因表达与心脑血管疾病的发生、发展密切相关。目前,探讨不同基因对心脑血管疾病血管生成的调控机制已成为当前研究的重点与热点。微小RNA-210(miR-210)作为基因类微小RNA(miRNA)当中一员,在血管生成的调控方面发挥着非常关键的作用,为缺血性心脑血管疾病早期的侧支循环建立提供了新的研究方向。The prevalence and mortality of ischemic cardiovascular and cerebrovascular diseases are increasing worldwide. More and more studies have shown that gene expression is closely related to the occurrence and development of cardiovascular and cerebrovascular diseases. At present,exploring the regulation mechanism of different genes on angiogenesis in cardiovascular and cerebrovascular diseases has become the focus and hotspot of current research. MicroRNA-210(miR-210),as one of the microRNAs(miRNA),plays a very critical role in the regulation of angiogenesis,providing new ideas for the establishment of collateral circulation in the early stage of ischemic cardiovascular and cerebrovascular diseases. Research direction.

关 键 词：MIR-210 缺血性心脑血管病 血管生成 

分 类 号：R259[医药卫生—中西医结合]