新兴技术在个体化漏斗胸Nuss手术规划中的应用发展  

Application progress of emerging techniques in patient-specific Nuss procedure for pectus excavatum

作　　者：罗苇如 熊吉文 刘金龙 刘锦纷[1,2,3] Luo Weiru;Xiong Jiwen;Liu Jinlong;Liu Jinfen(Department of Cardiothoracic Surgery,Shanghai Children’s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;Institute of Pediatric Translational Medicine,Shanghai Children’s Medical Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200127,China;Shanghai Engineering Research Center of Virtual Reality of Structural Heart Disease,Shanghai 200127,China)

机构地区：[1]上海交通大学医学院附属上海儿童医学中心心胸外科,上海200127 [2]上海交通大学医学院附属上海儿童医学中心儿科转化医学研究所,上海200127 [3]上海结构性心脏病虚拟现实工程技术研究中心,上海200127

出　　处：《中华胸心血管外科杂志》2022年第2期123-125,共3页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金(81970439);上海市科委国际学术合作交流项目(18410721400);上海市科委科技基金(17DZ2253100)。

摘　　要：漏斗胸是儿童常见的一种先天性胸部畸形,表现为前胸壁异常塌陷。在胸腔镜引导下的Nuss手术是目前广泛采用的一种临床治疗方案。术中因胸骨下方钢板的置入,易发生脏器损伤、术后疼痛、钢板移位、矫正不佳及钢板取出等问题。随着数字化精准医学及多学科多领域交叉研究的发展,以计算生物力学模拟仿真、3D打印及新型可降解生物材料为代表的新技术的临床应用和转化,为解决漏斗胸临床治疗中存在的问题,以及个体化Nuss手术规划的完善和发展带来了新的契机和前景。Pectus excavatum is a common congenital chest wall deformities in children,presented with abnormal collapse of anterior chest wall.Thoracoscopic Nuss procedure is the present widely utilized clinical approach.Due to implanting a steel bar into the substernal area,operative organ injuries,postoperative pain,bar malposition,incomplete correction as well as risks of bar removal may occur.With the advancement of digital precision medicine and the interdisciplinary research of various disciplines and fields,there are more and more clinical applications and translations of these emerging applications represented by computational biomechanical simulations,three-dimensional printing and the latest absorbable biomaterial.They bring new opportunities and prospects for solving problems in the clinical treatment of PE as well as the improvement and development of patient-specific Nuss procedure planning.

关 键 词：NUSS手术 漏斗胸 精准医学 临床治疗方案 脏器损伤 术后疼痛 3D打印 可降解生物材料 

分 类 号：R726.5[医药卫生—儿科]