吩嗪类化合物N-甲基化选择性研究  

Study on Selectivity of Methylation on Phenazine Compounds

作　　者：范颖[1] 刘懋 丛航[1] FAN Ying;LIU Mao;CONG Hang(Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province,Guizhou University,Guizhou Guiyang 550025,China)

机构地区：[1]贵州省大环化学及超分子化学重点实验室,贵州大学,贵州贵阳550025

出　　处：《广州化工》2022年第6期69-71,共3页GuangZhou Chemical Industry

基　　金：贵州省科学技术基金(No:20201Y028);贵州大学引进人才科研项目(No:201902)。

摘　　要：吩嗪及苯并[d]吩嗪在精细化学及材料化学中具有重要的潜在应用价值,由于其N-取代衍生化对该稠环化合物的电子结构及理化性质具有很大的影响,本文考察了吩嗪及苯并[d]吩嗪的N-甲基化反应的可能性,并结合底物分子结构,电子结构以及位阻作用等方面,对吩嗪、二苯并吩嗪以及四苯并吩嗪与硫酸甲酯的N-甲基化反应选择性进行了量子化学方法分析。Phenazine and dibenzophenazine have important potential applications if the fields of fine chemistry and materials chemistry,and the derivatization of nitrogen atom of the fused ring compound have great impact on their electronic structures and properties.The selectivity of N-methylation reaction of phenazine,dibenzophenazine,and dinaphthophenazine with methyl sulfate was evaluated,and the experimental results were explained with quantum chemical analysis of electronic structure and steric effect.

关 键 词：吩嗪 二苯并吩嗪 二萘并吩嗪 N-甲基化 

分 类 号：O626.4[理学—有机化学]