Evaluation the Properties of Polycaprolactone/Fluorapatite Nano-biocomposite  

作　　者：Mojtaba Momeni Kamran Amini Ali Heidari Mohammad Khodaei 

机构地区：[1]Department of Mechanical Engineering,Khomeinishahr Branch,Islamic Azad University,Khomeinishahr,84181-48499,Isfahan,Iran [2]Center for Advanced Engineering Research,Majlesi Branch,Islamic Azad University,86316-56451,Isfahan,Iran [3]Materials Engineering Group,Golpayegan College of Engineering,Isfahan University of Technology,87717-67498,Golpayegan,Iran

出　　处：《Journal of Bionic Engineering》2022年第1期179-187,共9页仿生工程学报（英文版）

摘　　要：In this study,nano-biocomposites of polycaprolactone(PCL)as the matrix and different amounts of nanofluorapatite(nFA)(0,10,20 and 30 wt.%)as the reinforcement were prepared for possible scaffold fabrication using the fused filament fabrication(FFF)3D printer.Field Emission Scanning Electron Microscopy(FE-SEM)and Energy Dispersive Spectroscopy(EDS)showed that nFA particles were well distributed in the PCL matrix.X-ray diffraction analysis(XRD)and Fourier Transform Infrared Spectroscopy(FTIR)depicted no chemical interaction between the elements of the composite.Differential Scanning Calorimetric(DSC)analysis was then used to assess the thermal properties of the composites,suggesting that this could be due to the amorphous phase formation of the intermolecular hydrogen bonds between PCL and nFA,resulting in the suppression of PCL crystallization.The results of mechanical characterization also showed that the addition of nFA up to 20 wt.%to the PCL increased the tensile and yield strength,as well as reducing the elongation at both yield and failure points and increasing the Young modulus.The best mechanical properties were obtained for the PCL/20nFA composite.Tensile strength and Young modulus were increased by 30%and 179%,respectively;meanwhile,elongation of PCL/20nFA was decreased by 70%,as compared to the naked PCL.These changes could be attributed to the better distribution of the nFA filler in the PCL matrix.According to the obtained results,PCL/20nFA could be regarded as a good composite in terms of the mechanical properties for the regeneration of the bone tissue.

关 键 词：Nano-biocomposite POLYCAPROLACTONE FLUORAPATITE Bone tissue engineering Mechanical properties 

分 类 号：R318.08[医药卫生—生物医学工程] TB383[医药卫生—基础医学]