Toxoplasma gondii infection in children after allogeneic hematopoietic stem cell transplantation: A case report and literature review  

作　　者：Lijuan Luo Nan Shen Wenjuan Chen Chengjuan Luo Xiaohang Huang Yuelian Jiang Qing Cao 

机构地区：[1]Department of Infectious Diseases,Shanghai Children’s Medical Center,School of Medicine,Shanghai Jiao Tong University,Shanghai,China [2]Department of Hematology and Oncology,Shanghai Children’s Medical Center,School of Medicine,Shanghai Jiao Tong University,Shanghai,China [3]Department of Pharmacy,Shanghai Children’s Medical Center,School of Medicine,Shanghai Jiao Tong University,Shanghai,China

出　　处：《Pediatric Investigation》2021年第3期239-243,共5页儿科学研究（英文）

基　　金：The Interdisciplinary Program of Shanghai Jiao Tong University(project number YG2021QN108)。

摘　　要：Introduction:Toxoplasmosis is a life-threatening complication after hematopoietic stem cell transplantation(HSCT).However,for several reasons,clinicians know little about Toxoplasma infection.Case presentation:We report a case of toxoplasmosis that was diagnosed by bone marrow smear and metagenomic next-generation sequencing(mNGS)after HSCT in a boy.Additionally,we summarize the characteristics of toxoplasmosis after pediatric HSCT reported in the literature published in PubMed.Conclusion:Clinicians should increase their awareness of toxoplasmosis in children after HSCT and implement pre-transplant screening and post-transplant monitoring and prevention in future according to the national conditions of our country.

关 键 词：TOXOPLASMOSIS Hematopoietic stem cell transplantation PEDIATRIC 

分 类 号：R725.3[医药卫生—儿科]