高血压病肝阳上亢证宏微观信息融合诊断量表阈值的建立  

Establishment of threshold of macro-micro information fusion diagnosis scale for hypertensive liver-yang hyperactivity syndrome

作　　者：李坤[1] 李运伦[1,2] 朱羽硕 LI Kun;LI Yun-lun;ZHU Yu-shuo(Shandong University of Traditional Chinese Medicine,Ji'nan 250014,China;The Affiliated Hospital of Shandong University of TCM,Ji'nan 250014.China)

机构地区：[1]山东中医药大学,济南250014 [2]山东中医药大学附属医院,济南250014

出　　处：《中华中医药杂志》2022年第2期693-697,共5页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81974566);山东省泰山学者建设工程专项经费(No.ts201712042)。

摘　　要：目的:建立高血压病肝阳上亢证宏微观信息融合诊断量表的阈值。方法:以符合研究标准的150例原发性高血压患者为研究对象,采用主客观综合赋权法,以德尔菲法和因子分析法分别确定主、客观权重系数,后将各指标的主客观权数相乘,并进行归一化处理得到目标组合权数,再利用受试者工作特征曲线(ROC曲线)确定最佳证候诊断阈值。结果:受试者ROC曲线的证候积分Y=243时,诊断量表最佳的敏感度为94.3%,特异度为95.2%。结论:高血压病肝阳上亢证宏微观信息融合诊断量表的证候积分≥243时,可诊断为肝阳上亢证。Objective: To establish the threshold of macroscopic and microscopic information fusion diagnostic scale for hypertension of liver-yang hyperactivity syndrome. Methods: Taking 150 patients with essential hypertension who meet the research criteria as the research object, the subjective and objective joint weighting method is used to determine the subjective and objective weighting coefficients by the Delphi method and the factor analysis method, and then the subjective and objective weights of each index are multiplied and normalized to obtain the target combination weights and then use the receiver operating characteristic curve(receiver operating characteristic curve, ROC curve) to determine the best syndrome diagnosis threshold.Results: When the syndrome score Y=243 of the receiver’s working characteristic curve, the optimal sensitivity of the diagnostic scale was 94.3%, and the specificity was 95.2%. Conclusion: When the syndrome score of the macro-micro information fusion diagnostic scale is ≥243, it can be diagnosed as hypertension of liver-yang hyperactivity.

关 键 词：高血压病 肝阳上亢证 宏微观信息融合 德尔菲法 因子分析法 受试者工作特征曲线 诊断量表阈值 

分 类 号：R259[医药卫生—中西医结合]