基于“寒温统一”理论的退热方治疗流行性感冒前瞻性非随机对照研究  

Prospective non-randomized controlled study of Tuire Formula in the treatment of influenza based on the theory of ‘cold and heat syndrome differentiation combination’

作　　者：苏芮 刘清泉[1] SU Rui;LIU Qing-quan(Beijing Hospital of Traditional Chinese Medicine,Capital Medical University,Beijing 100010,China)

机构地区：[1]首都医科大学附属北京中医医院,北京100010

出　　处：《中华中医药杂志》2022年第2期1164-1167,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家科技重大专项(No.2017ZX10305011)。

摘　　要：目的:观察基于“寒温统一”理论的退热方治疗流行性感冒(以下简称流感)的疗效。方法:针对60例流感患者开展前瞻性非随机对照研究,试验组予退热方联合奥司他韦,对照组予奥司他韦,均治疗5 d,观察比较两组患者流感症状评分、发热、咳嗽、咽痛缓解时间及退热药服用次数。结果:试验组流感症状评分在第4~7天显著低于对照组(P<0.05),流感症状缓解时间和咳嗽缓解时间显著低于对照组(P<0.05)。结论:退热方与奥司他韦联合使用能够明显缩短病程、改善症状,为外感热病“寒温统一”理论提供了临床依据。Objective: To study the effects and advantage of Tuire Formula treatment on influenza based on the theory of ‘cold and heat syndrome differentiation combination’. Methods: A prospective non-randomized controlled study was conducted on 60 patients with influenza. The experimental group was treated with Tuire Formula combined with Oseltamivir, and the control group was treated with Oseltamivir, each group was treated for 5 days. The score of influenza symptoms, and the alleviation time of fever, cough and pharyngeal pain, times of taking antipyretic drugs were assessed. Results: The score of influenza symptoms in the experimental group was significantly lower than that in the control group(P<0.05) at 4th to 7th day, time of first symptom alleviation and cough alleviation was significantly lower than that of the control group(P<0.05). Conclusion: The combination of Tuire Formula and traditional anti influenza drugs can significantly shorten the course of disease and improve symptoms, which also provides a clinical basis for the theory of ‘cold and heat syndrome differentiation combination’ for exogenous febrile diseases.

关 键 词：寒温统一 流行性感冒 病程 咳嗽缓解时间 退热方 前瞻性非随机对照研究 

分 类 号：R259[医药卫生—中西医结合]