陕西省ABO与Rh血型分布特征及人口迁移对血型分布的影响  

Distribution of ABO and Rh blood groups in Shaanxi Province and its formation by population migration

作　　者：孙杨[1] 申远 牛佳萌 邢莉莉 王李秦 王文华[4] 马婷[4] 杨江存[4] SUN Yang;SHEN Yuan;NIU Jiameng;XING Lili;WANG Liqin;WANG Wenhua;MA Ting;YANG Jiangcun(Data Centre,Shaanxi Provincial People's Hospital,Xi'an 710068;Department of Epidemiology and Biostatistics,School of Public Health,Xi'an Jiaotong University Health Science Centre,Xi'an 710061;Xi'an Medical University,Xi'an 710068;Department of Transfusion Medicine,Shaanxi Provincial People's Hospital,Xi'an 710068,China)

机构地区：[1]陕西省人民医院数据中心,陕西西安710068 [2]西安交通大学医学部公共卫生学院统计学教研室,陕西西安710061 [3]西安医学院临床检验诊断学专业,陕西西安710068 [4]陕西省人民医院输血科,陕西西安710068

出　　处：《细胞与分子免疫学杂志》2021年第11期1015-1021,共7页Chinese Journal of Cellular and Molecular Immunology

基　　金：陕西省人民医院领军人才项目(2021LJ-14)。

摘　　要：目的调查分析陕西人ABO和Rh血型的分布特征,探讨区域划分及人口迁移对血型分布的影响。方法收集陕西省十个地市20年3691624人献血者数据,以陕西省地理学特征分为陕北、陕南和关中3个地域,统计分析不同区域ABO及Rh血型分布特征。采用热图软件导入陕西省地图呈现ABO血型地图。分析对比2008年和2018年2个年份ABO血型分布时空变化特征。结果陕西人ABO血型分布特征为O>B>A>AB,Rh阴性占比为0.41%。绘制了陕西省ABO血型分布地图,陕西ABO血型分布有明显的地域差异,关中ABO血型分布为B>O>A>AB,陕南为O>A>B>AB,陕北为O>B>A>AB。陕北A型占比最低为26.12%,陕南B型最低为27.48%,O型在陕北和陕南地区占比较高,分别为32.60%和32.10%。与2008年相比,2018年的陕西三个区域ABO血型分布发生显著改变。结论陕西省ABO血型总体分布特征为O>B>A>AB,地域不同血型分布存在显著差异,1998~2018年间人口迁移对血型分布产生影响。Objective By investigating the distribution of ABO and Rh blood groups in Shaanxi Province, to discuss the influence of regional division and population migration on blood group distribution. Methods The data of 3 691 624 blood donors from 10 cities in Shaanxi province in the past 20 years was collected. According to the geographical characteristics of Shaanxi province, the data was divided into three regions: Northern Shaanxi, Southern Shaanxi, and Guanzhong, to statistically analyse the distribution of ABO and Rh blood groups across different regions. Heat map software was used to present the ABO blood group on Shaanxi map. The temporal and spatial characteristics of ABO blood group distribution during 2008 and 2018 were analysed and compared. Results ABO blood group distribution of Shaanxi people was O>B>A>AB, with a Rh negative ratio of 0.41%. Based on the ABO blood group distribution map of Shaanxi Province, obvious regional differences were found in ABO blood group distribution. The ABO blood group distribution in Guanzhong, Southern Shaanxi and Northern Shaanxi was B>O>A>AB, O>A>B>AB, and O>B>A>AB respectively, with the lowest proportion of type A being 26.12% in Northern Shaanxi, the lowest proportion of type B being 27.48% in Southern Shaanxi, and the highest proportion of type O being 32.60% and 32.10% in Northern Shaanxi and SouthernShaanxi respectively. Compared with 2008, the distribution of ABO blood groups in the three regions of Shaanxi province changed significantly in 2018.Conclusion The distribution of ABO blood group in Shaanxi province is O>B>A>AB in general. However, there are significant differences in blood group distribution among different regions. It was also found that population migration had an impact on blood group distribution from 1998 to 2018.

关 键 词：血型分布 ABO血型 RH血型 献血者 

分 类 号：R457.11[医药卫生—治疗学]