全国住院输血新生儿血气检测指标分析  

Blood Gas Indexes Changes in Hospitalized Neonates with Blood Transfusion in China

作　　者：王李秦 孙杨[2] 刘凤华[3] 谢昕昕[1] 马婷[1] 杨江存[1] WANG Li-qin;SUN Yang;LIU Feng-hua(Department of Transfusion Medicine,Shaanxi Provincial People's Hospital,Xi'an 710068)

机构地区：[1]陕西省人民医院输血科,710068 [2]陕西省人民医院数据中心 [3]哈尔滨医科大学第一附属医院输血科

出　　处：《临床输血与检验》2022年第2期170-175,共6页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：陕西省科技成果转移与推广计划-获奖成果转化项目(No.2020CGHJ-029);陕西省人民医院领军人才项目(No.2021LJ-14)资助。

摘　　要：目的调查全国住院输血新生儿血气检测指标,为深入研究不同阶段新生儿血气分析参考范围提供数据支持。方法本研究采用多中心回顾性调研方式,以全国46家医院2017年1月1日~2018年6月30日收治的输血新生儿5669例为研究对象,按照统一的数据采集表,采集新生儿住院诊治数据,对采集数据按胎龄分为<32 w组,32~36 w组,≥37 w组三组,统计分析新生儿住院期间输血干预前血气分析数据。结果随着新生儿日龄及胎龄的增大,pH值呈小幅波动,但总体呈升高的趋势。PO_(2)结果显示<32 w组随日龄增大呈降低趋势,≥37 w组自0~1 d(61.80 mmHg)升高至4~5 d(72.50 mmHg)后趋于平稳,相同日龄三组间PO_(2)值比较,日龄0~3 d时早产儿PO_(2)大于足月儿。PCO_(2)结果显示相同日龄三组间比较,随着胎龄的增大PCO_(2)逐渐降低。新生儿随着日龄和胎龄的增大,HCT值均呈逐渐降低的趋势。SaO_(2)结果显示≥37 w组自0~1 d(93%)升高至2~3 d(96.40%)后趋于稳定。结论不同胎龄不同日龄新生儿血气相关指标变化显著,依据胎龄日龄制定新生儿血气指标参考范围有助于指导临床对新生儿疾病的精准诊疗。Objective To investigate the blood gas indexes of hospitalized neonates with blood transfusion nationwide,and provide data support for in-depth research on the reference range of blood gas in newborns at different stages.Methods We conducted a multi-center retrospective study of 5669 newborns with blood transfusion admitted to 46 hospitals in China between January 1,2017 and June 30,2018 as the research objects.According to a unified data collection table,the diagnosis and treatment data of hospitalized newborns were collected.Based on the gestational age,these newborns were categorized into three groups:<32 w group,32~36 w group,and≥37 w group.The blood gas values were statistically analyzed.Results The pH value of newborns fluctuated slightly with the increase of gestational age and age,but the overall trend generally increased.PO_(2) showed that the<32 w group showed a decreasing trend with increasing age,and the≥37 w group increased from 0~1 day(61.80 mmHg)to 4~5 days(72.50 mmHg)and then stabilized.Comparison of PO_(2) among the three groups at the same age,PO_(2) in preterm infants was greater than that of full-term infants at 0~3 days.PCO_(2) showed that PCO_(2) gradually decreased with the increase of gestational age among the three groups at the same day.The HCT value showed a gradual decrease trend with the increase of day and gestational age.SaO_(2) showed that the≥37 w group increased from 0~1 day(93%)to 2~3 days(96.40%)and then stabilized.Conclusion Changes in blood gas related indexes of newborns with different gestational ages and days of ages were significant.The reference ranges of neonatal blood gas indexes based on gestational age can help guide the clinical accurate diagnosis and treatment of neonatal diseases.

关 键 词：新生儿 血气分析 参考范围 

分 类 号：R722.1[医药卫生—儿科]