Diagnostic Value of Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Patients with Severe COVID-19—7 PLADs,China,January 21–February 10,2020  

作　　者：Yan Ma Dongshan Zhu Nannan Shi Lei Zhang Guangkun Chen Youwen Ge Zelei Zhang Renbo Chen Sihong Liu Yipin Fan Huamin Zhang Yanping Wang 

机构地区：[1]Department of Infectious Disease Prevention,Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing,China [2]Department of Epidemiology,School of Public Health,Cheeloo College of Medicine,Shandong University,Jinan,Shandong Province,China [3]Centre for Health Management and Policy Research,School of Public Health,Cheeloo College of Medicine,Shandong University[NHC Key Lab of Health Economics and Policy Research(Shandong University)],Jinan,250012,China [4]Chinese Medicine Standardization Research Center,Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences,Beijing,China [5]Institute of Information on Traditional Chinese Medicine,China Academy of Chinese Medical Sciences,Beijing,China [6]Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,China.

出　　处：《China CDC weekly》2022年第10期195-198,I0001,共5页中国疾病预防控制中心周报（英文）

基　　金：Supported by“CACMS Innovation Fund(CI2021A00704);COVID-19 Project of National Administration of Traditional Chinese Medicine(2020ZYLCYJ07-1);COVID-19 project of National Administration of Traditional Chinese Medicine(GZY-KJS-2021-007);the Fundamental Research Funds for the Central public welfare research institutes(Z-0696)”.

摘　　要：Summary What is already known about this topic?Coronavirus disease 2019(COVID-19)causes symptoms ranging from mild to severe.Indicators for identifying severe COVID-19 infection have not been well identified,especially for young patients.What is added by this report?Both neutrophil-lymphocyte ratio(NLR)[area under curve(AUC):0.80;the odds ratios(OR)and 95%confidence intervals(95%CI):1.30(1.13–1.50)]and platelet-lymphocyte ratio(PLR)[AUC:0.87;OR(95%CI):1.05(1.01–1.09)]were determined to be indicators for recognition of patients with severe COVID-19 in young patients less than age 40.What are the implications for public health practice?NLR and PLR are useful indicators for identifying patients with severe COVID-19,especially in young patients less than age 40.

关 键 词：LYMPHOCYTE PATIENTS Platelet 

分 类 号：R563.1[医药卫生—呼吸系统]