机构地区:[1]广州市皮肤病防治所激光理疗科,广州510095
出 处:《国际医药卫生导报》2022年第7期1013-1016,共4页International Medicine and Health Guidance News
摘 要:目的探讨半导体激光联合30%超分子水杨酸治疗痤疮的疗效和护理效果。方法选取2019年10月至2021年4月在广州市皮肤病防治所就诊的100例痤疮患者,采用随机数字表法分为对照组与研究组,各50例。对照组男19例,女31例,年龄14~41(25.62±8.35)岁,给予半导体激光治疗;研究组男20例,女30例,年龄12~43(26.43±8.12)岁,给予半导体激光联合30%超分子水杨酸治疗。记录患者皮肤纹理特征变化、不良反应,并评估临床疗效及患者满意度;采用t检验、χ^(2)检验进行统计分析。结果治疗结束后,研究组色斑[(35.41±6.22)%比(40.16±9.37)%]、毛孔[(25.10±6.83)%比(29.65±8.40)%]、红斑[(21.05±8.42)%比(28.18±9.23)%]、紫质[(28.02±9.02)%比(32.60±10.67)%]计数均较对照组减少(t=2.986、2.972、4.035、2.318,均P<0.05);第2次治疗后研究组临床总有效率44.00%(22/50)均明显高于对照组24.00%(12/50),差异有统计学意义(χ^(2)=4.456,P=0.035),对照组与研究组治疗结束后2个月临床总有效率为54.00%(27/50)、78.00%(39/50),组间比较差异有统计学意义(χ^(2)=6.417,P=0.011);对照组与研究组痤疮总满意度为88.00%(44/50)、100.00%(50/50),组间比较差异有统计学意义(χ^(2)=8.542,P=0.004)。结论半导体激光联合30%超分子水杨酸治疗可显著改善痤疮症状,提高临床治疗效果和,同时应配合规范化护理措施,保障临床治疗效果和患者满意度。Objective To explore the effect of semiconductor laser combined with 30%supramolecular salicylic acid in the treatment of acne and the nursing effect.Methods A total of 100 patients with acne who were treated at the Guangzhou Institute of Dermatology Prevention and Treatment from October 2019 to April 2021 were selected and divided into a control group and a study group using a random number table method,with 50 cases in each group.The control group had 19 males and 31 females who were 14-41(25.62±8.35)years old,and were given semiconductor laser treatment.The study group had 20 males and 30 females who were 12 to 43(26.43±8.12)years old,and were treated with semiconductor laser and 30% supramolecular salicylic acid.The changes in skin texture characteristics and adverse reactions were recorded.The clinical efficacies and patient satisfaction were evaluated.t andχ^(2) tests were used for statistical analysis.Results After the treatment,the counts of stains,pores,erythema,and purple matter in the study group were lower than those in the control group[(35.41±6.22)%vs.(40.16±9.37)%,(25.10±6.83)%vs.(29.65±8.40)%,(21.05±8.42)%vs.(28.02±9.23)%,(29.31±9.02)%vs.(32.60±10.67)%;t=2.986,2.972,4.035,and 2.318;all P<0.05].After the second treatment,the total clinical effective rate was 44.00%(22/50)in the study group,and was 24.00%(12/50)in the control group,with a statistical difference(χ^(2)=4.456,P=0.035).The total effective rate 2 months after the end of the treatment was 54.00%(27/50)in the control group,and was 78.00%(39/50)in the study group,with a statistical difference(χ^(2)=6.417,P=0.011).The total satisfaction with acne was 88.00%(44/50)in the control group,and was 100.00%(50/50)in the study group,with a statistical difference(χ^(2)=8.542,P=0.004).Conclusions Semiconductor laser combined with 30%supramolecular salicylic acid can significantly improve the symptoms of acne and the clinical treatment effect.At the same time,standardized nursing measures should be used to ensure the clinical treatment eff
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