植物药材提取动力学研究进展及其标准化思考  

Research progress on extraction kinetics of plants and thinking of standardization

作　　者：白璧炜 闫广利 孙晖 白政忠 张清波 BAI Bi-wei;YAN Guang-li;SUN Hui;BAI Zheng-zhong;ZHANG Qing-bo(Research Center of Traditional Chinese Medicine Prescription Metabolomics,National Administration of Traditional Chinese Medicine,Heilongjiang University of Chinese Medicine,Harbin 150040,China;NMPA Key Laboratory for Quality Research and Evaluation of Traditional Chinese Medicine,Heilongjiang Institute for Drug Control,Harbin 150088,China)

机构地区：[1]黑龙江中医药大学,国家中医药管理局中医方证代谢组学研究中心,哈尔滨150040 [2]黑龙江省药品检验研究院,中药质量研究与评价重点实验室,哈尔滨150088

出　　处：《药物分析杂志》2022年第2期187-197,共11页Chinese Journal of Pharmaceutical Analysis

摘　　要：中药提取动力学是定量研究中药材有效成分、溶解规律和提取工艺的有利工具。随着动力学模型研究的由浅入深到简的发展过程,应用于药材提取工业化生产中的工艺参数日趋成熟,业界应加快提取动力学的标准化进程,以推进该工具的推广和应用。本文对国内近10年的植物药材提取动力学研究文献进行总结与归纳,对植物药材提取动力学研究和应用进行了深度思考并提出建议。对提取动力学研究的标准化和工具化具有非常现实的意义。The extraction kinetics of traditional Chinese medicine is a useful tool for quantitatively studying the dissolution rule and extraction process of the effective components.With the development process of kinetic model research from shallow to deep,and then from deep to simple,extraction kinetics is more beneficial to control the technological parameters in the industrial production of medicinal materials.The industry should accelerate the standardization process of extraction kinetics and promote the popularization and application of this tool.Through a summary of literature materials in the past ten years,thought deeply about the research and application of extraction kinetics of plant medicinal materials,then put forward suggestions.Standardization and instrumentalization of extraction dynamics research are of great practical significance.

关 键 词：植物 药材 提取 动力学 模型 应用 标准化 工具 成分 浸出 萃取 进展 

分 类 号：R917[医药卫生—药物分析学]