我国单细胞技术发展态势分析  

Development Trend Analysis of Single Cell Technology in China

作　　者：蒋甜 许哲平 尹传昊 陈学娟 朱学军[1] Jiang Tian;Xu Zheping;Yin Chuanhao;Chen Xuejuan;Zhu Xuejun(National Science Library,Chinese Academy of Sciences,Beijing 100190,China;Chinese Institute of Electronics,Beijing 100036,China)

机构地区：[1]中国科学院文献情报中心,北京100190 [2]中国电子学会,北京100036

出　　处：《科学观察》2022年第1期1-16,共16页Science Focus

基　　金：“中国科学院文献情报领域引进优秀人才计划”与“中国科学院A类战略性先导科技专项”(课题编号:XDA19050000);文化和旅游行业标准化研究项目(课题编号:WH/Y2020-03)的资助与支持。

摘　　要：[目的/意义]近年来,我国单细胞技术发展迅速,取得了许多突破性创新成果。全面了解我国单细胞技术发展态势,能为国家在单细胞技术领域的发展布局和战略规划提供参考。[方法/过程]通过科学计量与基金分析相结合的方法,对我国2009-2019年间单细胞技术相关的研究论文、专利和国家自然科学基金项目数据进行分析,系统呈现我国单细胞技术领域的发展现状和趋势。[结果/结论]研究结果表明,我国单细胞技术论文和专利在数量上占据绝对优势,但质量有待提高。国家自然科学基金对单细胞技术研发给予有力支持,我国企业在单细胞技术研发中发挥着越来越重要的作用。单细胞技术具有广阔的应用前景,呈现多学科交叉、全领域发展态势,单细胞检测分析平台、单细胞测序、肿瘤诊断和治疗、单细胞基因表达调控等是单细胞技术研究的热点。[Objective/Significance] In recent years, single cell technology has developed rapidly in China, and many breakthrough achievements have been made. A comprehensive understanding of the development trend of single cell technology in China can provide reference for the development layout and strategic planning of single cell technology in China. [Method/Process] Based on the research papers, patents and data of the National Natural Science Foundation of China(NSFC) in the field of single cell research from 2009 to 2019,the method of bibliometrics and fund analysis have been combined to detect the development status and trend of single cell research in China, in order to provide reference for researchers and management and decisionmaking departments. [Results/Conclusions] The results show that the number of papers and patents of single cell technology in China has absolute advantage, but the quality needs to be improved. The National Natural Science Foundation of China has given strong support to the research and development of single cell technology. Chinese enterprises are playing an increasingly important role in single cell technology research and development. Single cell technology has a broad application prospect, showing a trend of interdisciplinary development in the whole field. Single cell detection and analysis platform, single cell sequencing, tumor diagnosis and treatment, single cell gene expression regulation and so on are the hotspots of single cell technology research.

关 键 词：单细胞技术 文献计量分析 专利分析 国家自然科学基金 

分 类 号：Q2-3[生物学—细胞生物学] G353.1[文化科学—情报学]