加味当归补血汤联合琥珀酸亚铁片预防人工全膝关节置换术后失血性贫血临床研究  

Clinical Study on Modified Danggui Buxue Tang Combined with Ferrous Succinate Tablets for Prevention of Hemorrhagic Anemia After Total Knee Arthroplasty

作　　者：常守亚 张江涛 李启义 CHANG Shouya;ZHANG Jiangtao;LI Qiyi

机构地区：[1]河南省洛阳正骨医院(河南省骨科医院)膝部损伤三科,河南洛阳471002

出　　处：《新中医》2022年第4期29-31,共3页New Chinese Medicine

摘　　要：目的:观察加味当归补血汤联合琥珀酸亚铁片治疗人工全膝关节置换术后患者失血性贫血的临床效果。方法:选取人工全膝关节置换术患者120例作为研究对象进行前瞻性研究,按随机数字表法分为对照组和观察组各60例。对照组仅予以琥珀酸亚铁片治疗,观察组予以加味当归补血汤+琥珀酸亚铁片治疗。比较2组血红蛋白(Hb)、血小板计数(BPC)、红细胞比容(HCT)、膝关节、髋关节功能评分。结果:术前,2组Hb、HCT、BPC水平比较,差异无统计学意义(P>0.05)。治疗后,2组Hb、HCT水平较术前升高降低,BPC水平较术前升高;观察组Hb、HCT、BPC水平均高于对照组,差异均有统计学意义(P<0.05)。术前,2组膝关节HSS评分表(HSS)、Harris髋关节功能评分表(Harris)评分比较,差异无统计学意义(P>0.05);治疗后,2组HSS、Harris评分均较术前升高,且观察组HSS、Harris评分均高于对照组,差异均有统计学意义(P<0.05)。结论:加味当归补血汤联合琥珀酸亚铁片治疗人工全膝关节置换术后患者失血性贫血疗效显著,可有效改善其缺血性贫血指标,促进膝关节和髋关节的功能恢复。Objective:To observe the clinical effect of modified Danggui Buxue tang combined with ferrous succinate tablets for hemorrhagic anemia after total knee arthroplasty.Methods:A total of 120 cases of patients undergoing total knee arthroplasty were selected as subjects for prospective study,and were divided into the control group and the observation group according to the random number table method,with 60 cases in each group.The control group was simply treated with ferrous succinate tablets,and the observation group was treated with modified Danggui Buxue tang combined with ferrous succinate tablets.The hemoglobin(Hb),blood platelet count(BPC),hematocrit(HCT),and function scores of knee joint and hip joint in the two groups were compared.Results:Before surgery,there was no significant difference being found in the comparison of the levels of Hb,BPC and HCT between the two groups(P>0.05).After treatment,the levels of Hb and HCT in the two groups were decreased,while the levels of BPC in two group were increased when compared with those before surgery,and the levels of Hb,HCT and BPC in the observation group were higher than those in the control group,differences being significant(P<0.05).Before surgery,there was no significant difference being found in the comparison of the scores of HSS scale of knee joint(HSS) and Harris hip joint function scale(Harris) between the two groups(P>0.05).After treatment,the scores of HSS and Harris in the two groups were increased when compared with those before surgery,and the scores in the observation group were higher than those in the control group,differences being significant(P<0.05).Conclusion:The therapy of modified Danggui Buxue tang combined with ferrous succinate tablets for patients with hemorrhagic anemia after total knee arthroplasty has a significant clinical effect,and can improve the indexes of ischemic anemia and promote the recovery of knee joint and hip joint function.

关 键 词：人工全膝关节置换术 失血性贫血 加味当归补血汤 琥珀酸亚铁片 

分 类 号：R687.42[医药卫生—骨科学]