35%精甲霜·霜霉盐可溶液剂气相色谱分析方法研究  

Analysis of Metalaxyl-MoPropamocarb Hydrochloride 35% SL by GC

作　　者：王进 刘雪芬 潘光飞 廖文斌 林怡汝 张俊杰 Wang Jin;Liu Xuefen;Liao Wenbin;Lin Yiru;Zhang Junjie(Zhejiang Heben Pesticide&Chemicals Co.,Ltd.,Wenzhou 325008,China)

机构地区：[1]浙江禾本科技股份有限公司,浙江温州325008

出　　处：《云南化工》2022年第3期57-60,共4页Yunnan Chemical Technology

摘　　要：采用气相色谱法,以甲霜灵和霜霉威为标样,邻苯二甲酸二乙酯作为内标物,使用HP-5色谱柱和具有FID检测器的气相色谱仪对制剂中的有效成分精甲霜灵和霜霉威盐酸盐进行分离和定量分析。同时,采用液相色谱法,正己烷+异丙醇为流动相,使用CHIRALCEL OD-H手性柱,在210 nm检测波长下确定精甲霜灵中R-对映体的比例。结果得出,甲霜灵和霜霉威的线性相关系数分别为1.0000和0.9999;方法重复性的相对标准偏差分别为1.88%和1.69%,结果小于0.67×2^(1-0.5×lgc)(修订后Horwits公式)值;平均回收率分别为100.26%和99.53%。该方法操作简便,线性关系良好、准确度和精密度高,适用于产品质量控制及应用研究。Using gas chromatography, with metalaxyl and propamocarb as standard and diethyl phthalate as internal standard, HP-5 column and gas chromatograph with FID detector were used to determine the active ingredients in the preparation separation and quantitative analysis of metalaxyl-M and propamocarb hydrochloride. The proportion of R-enantiomers in metalaxyl-M was performed using CHIRALCEL OD-H chiral column at 210 nm and n-hexane and isopropanol was used as the mobile phase. The results showed that the linear coefficients of metalaxyl and propamocarb hydrochloride were 1.0000 and 0.9999, the coefficients of variations were 1.88% and 1.69% below the value of 0.67×2^(1-0.5×lgc)RSDr(Hor), and average recoveries rate were 100.26% and 99.53%, respectively. The method is a suitable analysis method with fast speed, good linear correlations, high precision and accuracy, and can be applied in both researches as well as product quality control.

关 键 词：化学分析 精甲霜灵 霜霉威盐酸盐 气相色谱 

分 类 号：K826.16[历史地理—历史学]