癌症患者放射性直肠炎预防和管理的最佳证据总结  

Summary of Best Evidence for Prevention and Management of Radiation Proctitis in Cancer Patients

作　　者：侯睿 岳延涛 王彬[1] 唐爱英 费晓燕[2] HOU Rui;YUE Yantao;WANG Bin;TANG Aiying;FEI Xiaoyan(Xuchang Central Hospital Affiliated to Henan University of Science and Technology,Xuchang,He'nan 461000;Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200025)

机构地区：[1]河南科技大学附属许昌市中心医院,河南许昌461000 [2]上海交通大学医学院附属瑞金医院,上海200025

出　　处：《上海护理》2022年第4期11-16,共6页Shanghai Nursing

基　　金：2019年度河南省医学科技攻关计划联合共建项目(LHGJ20191391)。

摘　　要：目的检索、评价并整合国内外关于癌症患者放射性直肠炎预防和管理的相关证据,并对最佳证据进行总结。方法系统检索BMJ Best Practice、UpToDate、JBI循证卫生保健中心数据库、国际指南协作网、美国国家指南库、英国国家卫生与临床优化研究所、苏格兰校际指南网、加拿大安大略注册护士协会网、中国临床指南文库、Cochrane Library、PubMed、美国国家综合癌症网络、万方数据库、中国知网、重庆维普数据库、中国生物医学文献数据库中所有关于放射性直肠炎预防和管理的证据,包括指南、专家共识、最佳实践、系统评价和证据总结。检索时限为2010年1月至2020年7月。采用澳大利亚JBI循证卫生保健中心的文献评价标准和证据分级系统,对文献进行质量评价及证据级别评定。结果共纳入15篇文献,其中指南2篇、专家共识3篇、临床决策2篇、系统评价8篇,总结了39条放射性直肠炎预防与管理证据,包括诊断与评估、预防、药物治疗、非药物治疗、手术治疗、营养治疗、中医治疗和调护8个方面。结论癌症患者放射性直肠炎预防与管理的最佳证据内容丰富,在应用时需要结合医院特点和临床环境,有针对性地选择,部分证据仍有待更高质量的研究加以证实。Objective To retrieve,evaluate and integrate relevant evidence on the prevention andmanagement of radiation proctitis in cancer patients at home and abroad,and to summarize the best evidence.Methods All evidence on the prevention and management of radiation proctitis,including guidelines,expertconsensuses,best practices,systematic reviews and evidence summaries,were retrieved from the followingsystems from January 2010 to July 2020:BMJ Best Practice,Up To Date,JBI EBP Database,GuidelinesInternational Network,National Guideline Clearinghouse,National Institute for Health and Clinical Excellence,Scottish Intercollegiate Guidelines Network,Registered Nurses’Association of Ontario website,ChinaGuideline Clearinghouse,Cochrane Library,Pub Med,National Comprehensive Cancer Network,Wanfang Data,CNKI,Chongqing VIP Database,and CBMdisc.The literature evaluation criteria and evidence grading systemof Joanna Briggs Institute in Australia were used to evaluate the quality of the articles and the level of evidence.Results A total of 15 articles were included,including 2 guidelines,3 expert consensuses,2 clinical decisionsand 8 systematic reviews,from which 39 pieces of evidence on the prevention and management of radiationproctitis were summarized to cover the following 8 aspects:diagnosis and evaluation,prevention,drug therapy,non-drug therapy,surgical therapy,nutritional therapy,TCM therapy,and care.Conclusion Abundant bestevidence on the prevention and management of radiation proctitis in cancer patients has been summarized.It should be used in combination with hospitalcharacteristics and clinical environment.Some ofthem still need to be confirmed in higher-qualitystudies.

关 键 词：癌症 患者 放射性直肠炎 预防 管理 循证护理学 

分 类 号：R47[医药卫生—护理学]