2-巯基噻唑啉低温热容的测定及热化学性质  

Determination of Heat Capacities of 2-Mercaptothiazoline in Low Temperature and Its Thermochemical Properties

作　　者：范杰 薛斌[1] FAN Jie;XUE Bin(School of Petrochemical Engineering,Shenyang University of Technology,Liaoyang Liaoning 111003,China)

机构地区：[1]沈阳工业大学石油化工学院,辽宁辽阳111003

出　　处：《当代化工》2022年第2期253-256,262,共5页Contemporary Chemical Industry

基　　金：国家自然科学基金(项目编号:21802014);中国博士后科学基金(项目编号:2020M670718)。

摘　　要：采用精密自动绝热量热仪器在80~400 K温度范围内测量纯度为0.9903摩尔分数的2-巯基噻唑啉的热容。结果证明,在测量温度范围内只有一个固-液熔化相变,通过计算可得2-巯基噻唑啉的熔化温度T_(m)、摩尔熔化焓Δ_(fus)H_(m)、摩尔熔化熵ΔfusSm值分别为377.49±0.02 K、12.07±0.02 kJ·mol^(-1)、31.97±0.04 J·K^(-1)·mol^(-1)。报道了在298.15~400 K的实验温度范围内,2-巯基噻唑啉以5 K为间距的热力学函数H(T)-H(298.15)、S(T)-S(298.15)、G(T)-G(298.15)值。采用差示扫描量热法测定样品的热容并与绝热量热法进行比较。通过使用热重分析法对2-巯基噻唑啉的热分解行为进行研究,得到了分解反应过程中2-巯基噻唑啉的相关动力学参数,为进一步应用2-巯基噻唑啉在药物合成和性质分析中提供了重要参考,其中反应级数n、频率因子A以及活化能E的值分别为1.78、1.150×10^(59) min^(-1)、603.8 kJ·mol^(-1)。The heat capacity of 2-mercaptothiazoline with a purity of 0.9903 mole fraction was measured using a precision automatic adiabatic thermal instrument in the temperature range of 80~400 K.The results showed that there was only one solid-liquid melting phase transition in the measured temperature range.The melting temperature Tm,molar melting enthalpyΔ_(fus)H_(m),and molar melting entropyΔfusSm values of 2-mercaptothiazoline were calculated,which were 377.49±0.02 K,11.44±0.02 kJ·mol^(-1),30.31±0.06 J·K^(-1)·mol^(-1),respectively.The thermodynamic function H(T)-H(298.15),S(T)-S(298.15),G(T)-G(298.15)values of 2-mercaptothiazoline at a temperature of 298.15~400 K every 5 K were reported.The heat capacity of sample was measured by differential scanning calorimetry and compared with that measured by adiabatic calorimetry.The thermal decomposition behavior of 2-mercaptothiazoline was characterized by thermal gravimetric analyzer.The relevant kinetic parameters during the decomposition reaction were calculated,which provided significant reference for the further application of 2-mercaptothiazoline in drug synthesis and analysis of property.The reaction order n,frequency factor A and activation energy E were 1.78,1.150×10^(59) min^(-1) and 603.8 kJ·mol^(-1),respectively.

关 键 词：2-巯基噻唑啉 量热法 低温热容 热力学函数 热分解 

分 类 号：O642[理学—物理化学]