冠状动脉溶栓在ST段抬高型心肌梗死中的研究进展  

Coronary Thrombolysis in ST-Segment Elevation Myocardial Infarction

作　　者：周星儿 赵施皓 郭宇婷 金荣杰 王继航[1,2] 王建 郭毅 田进文[1,2] 沈明志 ZHOU Xing’er;ZHAO Shihao;GUO Yuting;JIN Rongjie;WANG Jihang;WANG Jian;GUO Yi;TIAN Jinwen;SHEN Mingzhi(The Second School of Clinical Medicine,Sourthen Medical University,Guangzhou 510000,Guangdong,China;Department of Cardiology,Hainan Hospital of PLA General Hospital,Sanya 572013,Hainan,China)

机构地区：[1]南方医科大学第二临床医学院,广东广州510000 [2]解放军总医院海南医院心内科,海南三亚572013

出　　处：《心血管病学进展》2022年第3期229-231,240,共4页Advances in Cardiovascular Diseases

基　　金：海南省重点研发计划(ZDYF2020123,ZDYF2019188,ZDYF2017096)。

摘　　要：ST段抬高型心肌梗死是常见的心血管急危重症,致死率和致残率高。尽早实现心肌再灌注可有效挽救濒死心肌,改善ST段抬高型心肌梗死患者的预后,冠状动脉内溶栓在实现再灌注过程中发挥重要作用。现从血栓形成的机制、溶栓剂分类、冠状动脉内正向溶栓、血栓抽吸、血栓抽吸联合冠状动脉内溶栓、冠状动脉内逆向溶栓及应用前景等方面展开综述。ST-segment elevation myocardial infarction is a common emergent and critical cardiovascular disease with high mortality and disability rate.Early myocardial reperfusion can effectively save the dying myocardium and improve the prognosis of patients with ST-segment elevation myocardial infarction.Intracoronary thrombolysis plays an important role in the process of reperfusion.This article reviews the mechanisms of thrombogenesis,the classification of thrombolytic agents,intracoronary forward thrombolysis,thrombus aspiration,thrombus aspiration combined with intracoronary thrombolysis,intracoronary retrograde thrombolysis and its application prospect.

关 键 词：ST段抬高型心肌梗死 心肌再灌注 溶栓剂 冠状动脉内溶栓 

分 类 号：R54[医药卫生—心血管疾病]