逆行置管治疗恶性输尿管梗阻的多因素logistic回归分析  

Multivariate logistic regression analysis of retrograde ureteral stent for malignant ureteral obstruction

作　　者：赵勇 张旭 许志宏 施国洪 ZHAO Yong;ZHANG Xu;XU Zhihong;SHI Guohong(Department of Urology,First Hospital of Nanping City Affiliated to Fujian Medical University,Nanping,Fujian,353000,China)

机构地区：[1]福建医科大学附属南平第一医院泌尿外科,福建南平353000

出　　处：《临床泌尿外科杂志》2022年第2期133-137,145,共6页Journal of Clinical Urology

摘　　要：目的:分析影响逆行置管治疗恶性输尿管梗阻失败的主要危险因素。方法:回顾性分析2015年1月—2018年8月94例行逆行置管治疗的恶性输尿管梗阻患者的临床资料。对所研究的21个临床指标进行单因素分析,再将单因素分析中差异有统计学意义的相关因素进行多因素logistic回归分析。结果:对21项相关因素进行单因素分析,结果发现血清白蛋白水平、梗阻原因、膀胱浸润、肾积水程度、是否使用超滑导丝、CRF分级、腹膜后转移等7项之间的差异有统计学意义(P<0.05),再将上述7项相关因素作多因素logistic回归分析,统计结果显示血清白蛋白水平、梗阻原因、肾积水程度、未使用超滑导丝是影响逆行置管治疗恶性输尿管梗阻的主要危险因素。结论:患者血清白蛋白水平、梗阻原因、肾积水程度是影响逆行置管治疗恶性输尿管梗阻的主要危险因素,置管时使用超滑导丝是保护因素(OR=39.21)。Objective:To explore the main risk factors of retrograde ureteral stent failure in patients with malignant ureteral obstruction.Methods:The clinical date of 94 patients with malignant ureteral obstruction who underwent retrograde ureteral stenting between January 2015 and August 2018 were retrospectively analyzed.Univariate analysis was used in 21 clinical variables,then multivariate logistic regression analysis was used in the selected variables.Results:The results showed that there were statistically significant differences in serum albumin level,cause of obstruction,bladder invasion,level of hydronephrosis,unused super-slip guidewire,CRF classification and retroperitoneal metastasis(P<0.05).Then the above 7 relevant factors were subjected to the logistic multivariate regression analysis,and the results showed that the main risk factors for stent failure in patients with malignant ureteral obstruction who underwent retrograde ureteral stenting were serum albumin level,cause of obstruction,level of hydronephrosis and whether to use superslip guide wire.Conclusion:The main risk factors for stent failure in patients with malignant ureteral obstruction who underwent retrograde ureteral stenting were serum albumin level,cause of obstruction,level of hydronephrosis,whereas using super-slip guidewire is a protective factor(OR=39.21).

关 键 词：恶性输尿管梗阻 逆行置管 危险因素 

分 类 号：R693.2[医药卫生—泌尿科学]