无创正压通气和面罩给氧治疗病毒性肺炎合并Ⅰ型呼吸衰竭的疗效比较  

Comparison of efficacy of non-invasive positive pressure ventilation and mask oxygen inhalation in viral pneumonia complicated with type Ⅰ respiratory failure

作　　者：张国伟 杨京帆 ZHANG Guo-wei;YANG Jing-fan(Dianbai District People’s Hospital,Maoming 525000,China)

机构地区：[1]茂名市电白区人民医院,525000

出　　处：《中国实用医药》2022年第7期24-27,共4页China Practical Medicine

摘　　要：目的探讨比较病毒性肺炎合并Ⅰ型呼吸衰竭患者行无创正压通气(NIPPV)和面罩给氧的疗效。方法68例病毒性肺炎合并Ⅰ型呼吸衰竭患者,随机分为对照组和观察组,每组34例。对照组患者给予面罩给氧治疗,观察组患者给予无创正压通气治疗。对比两组患者不同时间点(上机时和上机24、48、96 h)动脉血氧分压(PaO_(2))和动脉血二氧化碳分压(PaCO_(2))水平。结果两组患者上机时和上机24 h的PaO_(2)水平对比差异均无统计学意义(P>0.05);观察组患者上机48 h和上机96 h的PaO_(2)分别为(61.52±9.95)、(69.34±9.38)mm Hg(1 mm Hg=0.133 kPa),明显高于对照组的(56.56±9.20)、(60.56±10.65)mm Hg,差异具有统计学意义(P<0.05)。两组患者上机时和上机24 h的PaCO_(2)水平对比差异均无统计学意义(P>0.05);观察组患者上机48 h和上机96 h的PaCO_(2)分别为(64.01±10.38)、(55.81±10.59)mm Hg,明显低于对照组的(69.54±10.74)、(61.54±11.74)mm Hg,差异具有统计学意义(P<0.05)。结论病毒性肺炎合并Ⅰ型呼吸衰竭患者实施无创正压通气,可有效改善血气指标,改善患者呼吸衰竭情况,在临床上具有较高的推广使用价值。Objective To discuss the efficacy of non-invasive positive pressure ventilation(NIPPV)and mask oxygen inhalation in viral pneumonia complicated with type Ⅰ respiratory failure.Methods A total of 68 patients with viral pneumonia and type Ⅰ respiratory failure were randomly divided into control group and observation group,with 34 cases in each group.Patients in the control group were treated with mask oxygen inhalation,and patients in the observation group were treated with non-invasive positive pressure ventilation.The levels of arterial partial pressure of oxygen(PaO_(2))and arterial partial pressure of carbon dioxide(PaCO_(2))were compared between the two groups at different time points(during treatment and 24,48 and 96 h after treatment).Results There was no statistically significant difference in PaO_(2) during treatment and 24 h after treatment between the two groups(P>0.05).The PaO_(2) of the observation group were(61.52±9.95)and(69.34±9.38)mm Hg(1 mm Hg=0.133 kPa)at 48 and 96 h after treatment,which were obviously higher than(56.56±9.20)and(60.56±10.65)mm Hg of the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in PaCO_(2) during treatment and 24 h after treatment between the two groups(P>0.05).The PaCO_(2) of the observation group were(64.01±10.38)and(55.81±10.59)mm Hg at 48 and 96 h after treatment,which were obviously lower than(69.54±10.74)and(61.54±11.74)mm Hg of the control group,and the difference was statistically significant(P<0.05).Conclusion Non-invasive positive pressure ventilation can effectively improve blood gas index and respiratory failure in patients with viral pneumonia and typeⅠrespiratory failure,and it contains high value of clinical promotion and application.

关 键 词：病毒性肺炎 Ⅰ型呼吸衰竭 无创正压通气 面罩给氧 疗效 

分 类 号：R563.8[医药卫生—呼吸系统] R563.1[医药卫生—内科学]