注水结肠镜下黏膜切除术治疗结直肠无蒂大息肉的临床效果和安全性研究  

Study on the clinical effect and safety of underwater endoscopic mucosal resection in the treatment of large colorectal sessile polyps

作　　者：张镕宇 刘宇虎[1] 陈桂权[1] 詹磊磊[1] 郭伟仪 ZHANG Rong-yu;LIU Yu-hu;CHEN Gui-quan(Department of Gastroenterology,Dongguan People’s Hospital,Dongguan 523000,China)

机构地区：[1]东莞市人民医院消化内科,523000

出　　处：《中国实用医药》2022年第7期46-48,共3页China Practical Medicine

基　　金：东莞市社会科技发展项目(项目编号:201950715001225)。

摘　　要：目的探讨注水结肠镜下黏膜切除术(UEMR)治疗结直肠无蒂大息肉的临床效果和安全性。方法1000例结直肠无蒂大息肉患者,依照手术方法不同分为对照组及实验组,每组500例。对照组给予常规切除术治疗,实验组给予注水结肠镜下黏膜切除术治疗。比较两组患者临床疗效及术后并发症发生情况。结果实验组患者的总有效率为99.20%(496/500),显著高于对照组的85.60%(428/500),差异有统计学意义(P<0.05)。实验组患者的术后并发症发生率1.60%低于对照组的4.80%,差异具有统计学意义(P<0.05)。结论注水结肠镜下黏膜切除术治疗结直肠无蒂大息肉的疗效确切,具有更高的安全性,值得在临床实践中大力推广实施。Objective To discuss the clinical effect and safety of underwater endoscopic mucosal resection(UEMR)in the treatment of large colorectal sessile polyps.Methods A total of 1000 patients with large colorectal sessile polyps were divided into control group and experimental group according to different surgical methods,with 500 cases in each group.The control group was treated with conventional resection,and the experimental group was treated with underwater endoscopic mucosal resection.The clinical efficacy and postoperative complications were compared between the two groups.Results The total effective rate of patients in the experimental group was 99.20%(496/500),which was significantly higher than 85.60%(428/500)in the control group,and the difference was statistically significant(P<0.05).The postoperative complication rate 1.60% in the experimental group was lower than 4.80% in the control group,and the difference was statistically significant(P<0.05).Conclusion Underwater endoscopic mucosal resection is effective in the treatment of large colorectal sessile polyps,and has high safety,which is worthy of promotion in clinical practice.

关 键 词：注水结肠镜下黏膜切除术 结直肠无蒂大息肉 常规切除术 

分 类 号：R656.9[医药卫生—外科学]