一起可能经气溶胶传播的新型冠状病毒Delta变异株聚集性疫情调查  

Survey of possible aerosol transmission of a COVID-19 epidemic caused by 2019-nCoV Delta variant

作　　者：吴双胜[1] 张姣姣 孙瑛[1] 任正勇 窦相峰[1] 张莉[1] 段玮[1] 马春娜[1] 杨鹏[2] 庞星火[3] Wu Shuangsheng;Zhang Jiaojiao;Sun Ying;Ren Zhengyong;Dou Xiangfeng;Zhang Li;Duan Wei;Ma Chunna;Yang Peng;Pang Xinghuo(Institute for Infectious Disease and Endemic Disease Control,Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine,Beijing 100013,China;Office of Global Health Center,Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine,Beijing 100013,China;Central Office,Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine,Beijing 100013,China)

机构地区：[1]北京市疾病预防控制中心传染病地方病控制所/北京市预防医学研究中心,北京100013 [2]北京市疾病预防控制中心全球健康中心办公室/北京市预防医学研究中心,北京100013 [3]北京市疾病预防控制中心办公室/北京市预防医学研究中心,北京100013

出　　处：《中华流行病学杂志》2022年第3期305-309,共5页Chinese Journal of Epidemiology

基　　金：北京市科技计划(Z211100002521019,Z211100000221019)。

摘　　要：目的分析北京市昌平区一起新型冠状病毒(新冠病毒)Delta变异株家庭聚集性疫情的流行特征和传播链。方法应用流行病学调查和大数据技术核查病例的活动轨迹,对活动轨迹涉及的风险点位进行密切接触者追踪、人员和环境采样核酸检测,对核酸阳性标本进行基因测序分析。结果2021年11月1日,通过人群主动筛查,发现北京市昌平区一起涉及5例新冠病毒感染者的Delta变异株家庭聚集性疫情。感染来源于10月22-27日与该起家庭聚集性疫情的首发病例在同一酒店集中隔离。感染来源在隔离期间可能通过通风管道气溶胶传播给该起疫情的首发病例。首发病例10月27日解除隔离,10月27日至11月1日在共同居住期间造成其他4名家庭成员续发感染。结论新冠病毒Delta变异株易引发家庭聚集性疫情,隔离酒店上下通风管道传播应引起重视。Objective To investigate the epidemiological characteristics and the transmission chain of a family clustering of COVID-19 cases caused by severe acute respiratory 2019-nCoV Delta variant in Changping district of Beijing.Methods Epidemiological investigation was conducted and big data were used to reveal the exposure history of the cases.Close contacts were screened according to the investigation results,and human and environmental samples were collected for nucleic acid tests.Positive samples were analyzed by gene sequencing.Results On November 1,2021,a total of 5 COVID-19 cases caused by 2019-nCoV Delta variant were reported in a family detected through active screening.The infection source was a person in the same designated isolation hotel where the first case of the family cluster was isolated from 22 to 27,October.The first case was possibly infected through aerosol particles in the ventilation duct system of the isolation hotel.After the isolation discharge on October 27,and the first case caused secondary infections of four family members while living together from October 27 to November 1,2021.Conclusion 2019-nCoV Delta variant is prone to cause family cluster,and close attention needs to be paid to virus transmission through ventilation duct system in isolation hotels.

关 键 词：新型冠状病毒肺炎 新型冠状病毒 Delta变异株 气溶胶 感染来源 

分 类 号：R563.1[医药卫生—呼吸系统] R181.8[医药卫生—内科学]