流感疫苗在高危人群中应用安全性、有效性及接种现状研究新进展  

Progress in research of safety,efficiency and vaccination status of influenza vaccine in populations at high risk

作　　者：随海田 郭洋 赵杰 杨中楠 苏锦锋 杨媛 王晴[3] 冯录召 Sui Haitian;Guo Yang;Zhao Jie;Yang Zhongnan;Su Jinfeng;Yang Yuan;Wang Qing;Feng Luzhao(China National Biotec Group Company Limited,Beijing 100024,China;Division of Infectious Diseases,Chinese Center for Disease Control and Prevention,Beijing 102206,China;School of Population Medicine and Public Health,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China)

机构地区：[1]中国生物技术股份有限公司,北京100024 [2]中国疾病预防控制中心传染病管理处,北京102206 [3]中国医学科学院北京协和医学院群医学及公共卫生学院,北京100730

出　　处：《中华流行病学杂志》2022年第3期436-439,共4页Chinese Journal of Epidemiology

摘　　要：对2020年国内外不同高危人群流感疫苗应用情况发表的相关研究进展进行综述。流感疫苗在高危人群中接种的重要性得到了更多大样本、多中心、高质量循证证据的支持。接种流感疫苗是预防流感最经济有效的措施,目前我国流感疫苗接种率很低,需进一步加大对各类人群流感疫苗接种的科普宣传与教育。建议流感季来临前对研究证据明确的疫苗接种安全有效的人群接种流感疫苗,对于目前缺乏研究证据或者研究证据不足的人群,需加快开展流感疫苗接种安全性和有效性、成本效益等方面的研究。This paper reviews the domestic and foreign studies published in 2020 on the application of influenza vaccine in populations at high risk.The importance of influenza vaccination in population at high risk has been proved by larger sample,multicentre,high-quality evidence-based studies.Influenza vaccination is the most cost-effective measure to prevent influenza.However,the coverage rate of influenza vaccine is very low in China,it is necessary to strengthen the health education to promote influenza vaccination in different populations.It is recommended to give influenza vaccination to the population in whom influenza vaccination has been proven safe and effective before influenza season.Research of the safety,efficiency and cost-effectiveness of influenza vaccine should be accelerated for the populations in whom such data are lacking or insufficient.

关 键 词：流感疫苗 安全性 有效性 接种现状 

分 类 号：R186[医药卫生—流行病学]