急性心肌梗死患者并发左心室收缩功能不全的危险因素分析  

Analysis of risk factors of left ventricular systolic insufficiency in patients with acute myocardial infarction

作　　者：赵洲锋 郭飞坤 ZHAO Zhou-feng;GUO Fei-kun(Dafeng Hospital,Chaoyang District,Shantou 515154,China)

机构地区：[1]汕头市潮阳区大峰医院心血管内科,广东汕头515154

出　　处：《中国处方药》2022年第3期164-166,共3页Journal of China Prescription Drug

摘　　要：目的探讨急性心肌梗死患者并发左心室收缩功能不全的危险因素。方法以2018年6月~2020年6月收治的94例急性心肌梗死患者为研究对象,将其中合并左心室收缩功能不全的45例患者纳入A组,其余49例左心室收缩功能正常的患者纳入B组,回顾性分析两组临床资料,Logistic回归分析急性心肌梗死患者并发左心室收缩功能不全的危险因素。结果A组吸烟史、冠脉介入/搭桥史、冠脉病变≥3支患者占比高于B组,血hs-CRP、WBC、NLR以及LVEDd、EAT与冠脉Gensini评分高于B组,差异有统计学意义(P<0.05)。经Logistic回归分析,冠脉病变数≥3支、NLR与冠脉Gensini评分是急性心肌梗死并发左心室功能收缩不全的独立危险因素。结论对于冠脉病变数≥3支、Gensini评分高的急性心肌梗死患者,临床应高度警惕左心室收缩功能不全,NLR可以为临床预测急性心肌梗死并发左心室收缩功能不全提供重要的实验室依据,早期检测NLR对指导临床救治具有积极作用。Objective To explore the risk factors of left ventricular systolic insufficiency in patients with acute myocardial infarction.Methods Taking 94patients with acute myocardial infarction admitted to our hospital from June 2018 to June 2020 as the research objects,45 patients with left ventricular systolic insufficiency were included in group A.49 patients with normal left ventricular systolic function were included in group B.The clinical data of the two groups were retrospectively analyzed,and the risk factors of left ventricular systolic insufficiency in patients with acute myocardial infarction were analyzed by Logistic regression.Results The proportion of patients with smoking history,coronary intervention/bypass history,coronary artery disease≥3 vessels was higher in group A than in group B,blood hs-CRP,WBC,NLR,LVEDd,EAT,and coronary Gensini scores were higher than those in group B,and the difference was statistically significant(P<0.05).Logistic regression analysis showed that the number of coronary artery lesions≥3,NLR and coronary Gensini score were independent risk factors for acute myocardial infarction complicated with left ventricular insufficiency.Conclusion For patients with acute myocardial infarction with more than 3 coronary artery lesions and a high Gensini score,the clinic should be highly vigilant about left ventricular systolic insufficiency.NLR can provide important laboratory evidence for clinical prediction of acute myocardial infarction complicated with left ventricular systolic insufficiency.The detection of NLR has a positive effect on guiding clinical treatment.

关 键 词：急性心肌梗死 左室收缩功能不全 危险因素 

分 类 号：R542.22[医药卫生—心血管疾病]