无水乙醇局部注射治疗慢性结核性脓胸的效果  

The efficacy of local injection of anhydrous ethanol in the treatment of chronic tuberculous empyema

作　　者：李淑英 聂琦 李彩红 LI Shuying;NIE Qi;LI Caihong(Department of General Medicine,the Sixth Hospital of Wuhan,Affiliated Hospital of Jianghan University,Hubei,Wuhan 430000,China;Undergraduate Ward of Wuhan Jinyintan Hospital,Hubei,Wuhan 430000,China)

机构地区：[1]江汉大学附属医院武汉市第六医院综合科,湖北武汉430000 [2]武汉市金银潭医院大学生病房,湖北武汉430000

出　　处：《中国医药科学》2022年第5期179-181,185,共4页China Medicine And Pharmacy

基　　金：湖北省武汉市卫生和计划生育委员会科研项目(WX17Q28)。

摘　　要：目的观察局部注射无水乙醇治疗慢性结核性脓胸的疗效。方法选取2017年11月至2019年9月武汉市金银潭医院大学生病房120例慢性结核性脓胸住院患者,随机分为Y+C组和C组,每组60例。C组脓肿用5%碳酸氢钠冲洗,Y+C组脓腔注入无水乙醇,对比两组患者的治疗效果、症状缓解时间及脓腔闭合时间、治疗前后胸膜厚度以及并发症发生情况。结果Y+C组的总有效率高于C组,差异有统计学意义(P<0.05);Y+C组缓解症状和关闭脓腔所需的时间少于C组,差异有统计学意义(P<0.05);Y+C组治疗后胸膜厚度少于C组,差异有统计学意义(P<0.05);Y+C组术后穿刺伤口明显疼痛46例、头晕及皮肤发红2例,均可耐受且均自行缓解。结论胸腔注射无水乙醇比碳酸氢钠治疗慢性结核性脓胸更有效,能够显著提升临床治疗效率,改善胸膜厚度,降低并发症的发生率,并且缩短缓解症状和关闭脓腔所需的时间,值得实施和开展。Objective To observe the efficacy of local injection of anhydrous ethanol in the treatment of chronic tuberculous empyema.Methods A total of 120 inpatients with chronic tuberculous empyema in the Undergraduate Ward of Wuhan Jinyintan Hospital from November 2017 to September 2019 were selected and randomly divided into group Y+C and group C,with 60 cases in each group.Group C was treated with 5%sodium bicarbonate for empyema flushing,while group Y+C was injected with anhydrous ethanol via the pus cavity.The efficacy,symptom remission time and pus cavity closure time,pleural thickness before and after treatment,and the occurrence of complications were compared between the two groups.Results The overall effective rate of group Y+C was higher than that of group C,with statistically significant difference(P<0.05).The time required for symptom remission and pus cavity closure in group Y+C was less than that in group C,with statistically significant differences(P<0.05).The pleural thickness in group Y+C was thinner than that in group C after treatment,with statistically significant difference(P<0.05).46 cases had obvious pain in the puncture wound,and 2 cases had dizziness and erythema in group Y+C,all of whom were tolerable and resolved on their own.Conclusion In the treatment of chronic tuberculous empyema,thoracic injection of anhydrous ethanol is more effective than baking soda in significantly upgrading clinical treatment efficiency,improving pleural thickness,reducing the incidence of complications,and shortening the time required for symptom remission and pus cavity closure.Therefore,it is worthy of implementation.

关 键 词：结核性脓胸 慢性脓胸 无水乙醇 碳酸氢钠 

分 类 号：R521[医药卫生—内科学]