磁敏感加权成像检查+氢质子磁共振波谱成像对脑胶质瘤分级诊断效能的影响  

Effect of Susceptibility-weighted Imaging Combined with Proton Magnetic Resonance Spectroscopy on the Diagnostic Performance of Glioma Grading

作　　者：崔振华[1] CUI Zhen-hua(MRI Room of Imaging Department,Anyang Cancer Hospital,Anyang,Henan,455000,China)

机构地区：[1]安阳市肿瘤医院影像科核磁共振室,河南安阳455000

出　　处：《黑龙江医学》2022年第6期743-744,747,共3页Heilongjiang Medical Journal

摘　　要：目的:研究磁敏感加权成像(SWI)检查+氢质子磁共振波谱(1H-MRS)成像对脑胶质瘤分级的诊断效能。方法:选取2019年5月—2020年5月安阳市肿瘤医院脑收治的94例胶质瘤患者,均行SWI、1H-MRS检查,以世界卫生组织(WHO)分级方法为“金标准”。比较脑胶质瘤不同分级的SWI、1H-MRS检查参数[磁敏感信号(ITSS)评分、胆碱化合物(Cho)/肌酸(Cr)、N-乙酰天门冬氨酸(NAA)/Cr、NAA/Cho],比较SWI、1H-MRS检查及联合检查脑胶质瘤分级的诊断结果及诊断效能(灵敏度、特异度、准确度)。结果:不同脑胶质瘤分级NAA/Cho比较,差异无统计学意义(P>0.05);高级脑胶质瘤患者ITSS评分、Cho/Cr高于低级患者,NAA/Cr低于低级患者,差异有统计学意义(t=13.989,17.845,12.675,P<0.05);联合检查高级脑胶质瘤灵敏度93.75%高于SWI检查70.83%、1H-MRS检查72.92%,差异有统计学意义(χ^(2)=9.347,P<0.05);联合检查高级脑胶质瘤特异度为82.61%、准确度为88.30%,SWI检查特异度为86.96%、准确度为78.72%,1H-MRS检查特异度为84.78%、准确度为78.72%,三者比较差异无统计学意义(P>0.05)。结论:SWI检查+1H-MRS成像能准确区分高、低级脑胶质瘤,提高诊断效能,有助于临床治疗方案的制定。Objective:To study the diagnostic performance of susceptibility-weighted imaging (SWI) plus hydrogen proton magnetic resonance spectroscopy (1H-MRS) imaging for grading gliomas.Methods:A total of 94 patients with glioma who were admitted to the hospital from May 2019 to May 2020 were selected and underwent SWI and 1H-MRS examinations. The World Health Organization (WHO) grading method was used as the “gold standard”. SWI and 1H-MRS examination parameters of different grades of gliomas (magnetic sensitivity signal [ITSS] score, choline compound [Cho]/creatine [Cr], N-acetylaspartic acid [NAA]/Cr, NAA /Cho) were compared. The diagnostic results and diagnostic performance (sensitivity, specificity, and accuracy) of SWI, 1H-MRS and combined glioma grading were compared.Results:There was no statistically significant difference in NAA/Cho among differen glioma grades, with statistically significant difference (P>0.05). The ITSS score and Cho/Cr of high-grade glioma patients were higher than those of low-grade patients, and the NAA/Cr was lower than that of low-grade patients, with statistically significant difference (t=13.989, 17.845, 12.675, P<0.05). The sensitivity of combined examination of high-grade glioma was 93.75% higher than 70.83% of SWI examination and 72.92% of 1H-MRS examination, with statistically significant difference (χ^(2)=9.347, P<0.05)The specificity and accuracy of combined examination of high-grade glioma were 82.61% and 88.30%, the specificity and accuracy of SWI examination were 86.96% and 78.72% , and the specificity and accuracy of 1H-MRS examination were 84.78% and78.72% . There was no statistically significant difference between the two groups (P>0.05).Conclusion:SWI examination +1H-MRS imaging can accurately distinguish high-grade and low-grade gliomas, improve the diagnostic efficiency, and contribute to the formulation of clinical treatment plans.

关 键 词：磁敏感加权成像 氢质子磁共振波谱 脑胶质瘤分级 诊断效能 

分 类 号：R445.2[医药卫生—影像医学与核医学]