肾脏低温机械灌注与静态冷保存的经济学对比分析  

Comparative analysis of economics of hypothermic mechanical perfusion versus static cold preservation for kidney transplantation

作　　者：郎治权 余斌 王彦峰[1] Lang Zhiquan;Yu Bin;Wang Yanfeng(Department of Transplantation,Zhongnan Hospital of Wuhan University,Institute of Hepatobiliary Diseases of Wuhan University,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院器官移植科武汉大学肝胆疾病研究院,武汉430071

出　　处：《中华器官移植杂志》2022年第3期161-165,共5页Chinese Journal of Organ Transplantation

基　　金：武汉大学中南医院科技创新平台支撑项目(PTXM2022004)。

摘　　要：目的评价国内外文献报道的肾脏低温机械灌注(HMP)与静态冷保存(CS)的医疗费用,为临床决策提供参考。方法检索PubMed、CENTRAL(Cochrane Library)、Web of Science、EMBASE、CNKI、万方等所有肾脏HMP与CS的医疗费用对比的文献。根据纳入和排除标准对搜索到的文献进行筛选以确定符合条件的文献。提取并分析文献中HMP和CS费用的数据,以描述性方式报告结果。结果共纳入10篇报道HMP和CS费用的文献。结果显示,在扩大标准供肾组中,HMP相比CS首次住院费用更低。HMP相比CS可能长期费用更低。其费用低可能与移植肾功能延迟(DGF)发生率降低有关。结论HMP可以带来医学和经济学效益,HMP相比CS的费用优势可能与供肾质量改善以及DGF发生率降低有关。Objective An assessment of domestic and foreign literatures regarding the medical expenses of kidney hypothermic machine perfusion(HMP)versus cold storage(CS)to provide guidance for clinical decision-making.Methods Relevant literatures were retrieved from PubMed,CENTRAL(Cochrane Library),Web of Science,EMBASE,CNKI,Wanfang,etc.The literatures and according data were finally enrolled based on the inclusion and exclusion criteria.The results were reported descriptively.Results A total of 10 literatures reporting the costs of HMP and CS were included.The results show that HMP can reduce the cost of first hospitalization compared with CS in expanded criteria donor.HMP may also reduce long-term costs compared to CS.The lower cost may be associated with the lower incidence of delayed graft function(DGF).Conclusions HMP may bring medical and economic benefits to patients.The cost advantage of HMP over CS may be related to the improved quality of donor kidney and a lower incidence of DGF.

关 键 词：肾移植 低温机械灌注 器官保存 

分 类 号：R699.2[医药卫生—泌尿科学] R1[医药卫生—外科学]