胎儿先天性心脏病危险因素及治疗方式研究进展  

Research on the risk factors and treatment in fetal congenital heart disease

作　　者：马海霞 张国英[1] 陈黎[1] 余梅 MA Haixia;ZHANG Guoying;CHEN Li;YU Mei(Obstetrics Department of the First Affiliated Hospital with Nanjing Medical University,Nanjing,Jiangsu 210029,China)

机构地区：[1]南京医科大学第一附属医院产科,江苏南京210029

出　　处：《中国优生与遗传杂志》2021年第12期1791-1795,共5页Chinese Journal of Birth Health & Heredity

摘　　要：胎儿先天性心脏病(CHD)即孕期发现的胎儿心脏异常,并由简单型到复杂型不同程度影响胎儿或新生儿结局,是出生缺陷死亡的重要原因之一。CHD的危险因素包括多个方面,其中遗传因素导致的CHD往往复杂且严重,需要尽早干预并决策。随着临床药物和介入治疗等技术的进步,越来越多的先天性心脏病胎儿得到救治,但存活下来的患儿其神经发育和生长状态等方面仍然面临巨大挑战。本文以此为背景,结合国内外研究,对胎儿先天性心脏病的危险因素、治疗方式及主要预后结局进行综述。Fetal congenital heart disease(CHD) refers to fetal heart abnormalities detected during pregnancy, which affects fetal or neonatal outcomes depending on the complexity of the disease. CHD is an important cause of death due to birth defects. CHD is caused by many risk factors, and genetic factor is more complex and serious, early intervention and decision are required. With the development of invasive therapy, a large number of fetuses with CHD were saved. However, there are huge challenges having to face for the surviving children about their neurological development and growth status. In this review, the risk factors, treatment and outcomes of fetal congenital heart disease were discussed.

关 键 词：胎儿先天性心脏病 危险因素 治疗 预后 

分 类 号：R714.5[医药卫生—妇产科学]