中药三圣汤联合腰背肌功能锻炼治疗肝肾亏虚夹瘀型腰椎术后综合征的疗效观察  

Therapeutic Effect of Chinese Medicine Sansheng Decoction Combined with Lumbodorsal Muscle Exercise in the Treatment of Failed Back Surgery Syndrome with Insufficiency of Liver and Kidney Interweaved with Blood Stasis Type

作　　者：王伟群 吴俊哲 苏培基 池伟东 周兴茂 张彬 WANG Wei-Qun;WU Jun-Zhe;SU Pei-Ji;CHI Wei-Dong;ZHOU Xing-Mao;ZHANG Bin(Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine,Zhongshan 528400 Guangdong,China)

机构地区：[1]广州中医药大学附属中山中医院,广东中山528400

出　　处：《广州中医药大学学报》2022年第4期794-799,共6页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中山市科学技术局科研项目(编号:2019B1069)。

摘　　要：【目的】观察中药汤剂三圣汤联合腰背肌功能锻炼治疗肝肾亏虚夹瘀型腰椎术后综合征的临床疗效。【方法】将36例肝肾亏虚夹瘀型腰椎术后综合征患者随机分为观察组和对照组,每组各18例。2组患者均给予术后腰背肌功能锻炼,在此基础上,对照组给予口服塞来昔布胶囊的常规治疗,观察组在对照组基础上给予中药汤剂三圣汤治疗,治疗4周为1个疗程,连续治疗3个疗程。观察2组患者治疗前后腰椎疼痛数字评价量表(NRS)评分和腰部功能Oswestry障碍指数(ODI)评分的变化情况,并评价2组患者的临床疗效和安全性。【结果】(1)治疗3个月后,观察组的总有效率为94.4%(17/18),对照组为77.8%(14/18),组间比较,观察组的临床疗效明显优于对照组,差异有统计学意义(P<0.05)。(2)治疗2周、2个月和3个月后,2组患者的NRS评分和ODI评分均较治疗前降低(P<0.05),且随着治疗时间的延长,对NRS评分和ODI评分的降低作用越明显;组间比较,观察组在治疗3个月后的NRS评分和ODI评分均明显低于对照组,差异均有统计学意义(P<0.05)。(3)治疗过程中,2组患者均未出现皮肤血肿、灼伤、感染、腹泻和腰痛腿麻症状加重等不良反应情况。【结论】中药三圣汤联合腰背肌功能锻炼治疗肝肾亏虚夹瘀型腰椎术后综合征患者疗效确切,能有效缓解患者腰腿痛症状,提高患者术后生活质量,且安全性较好,可为临床治疗腰椎术后综合征提供新的治疗思路。Objective To observe the clinical efficacy of Sansheng Decoction combined with lumbodorsal muscle exercise in the treatment of failed back surgery syndrome(FBSS)with insufficiency of liver and kidney interweaved with blood stasis type.Methods Thirty-six FBSS patients with insufficiency of liver and kidney interweaved with blood stasis type were randomly divided into observation group and control group,with 18 cases in each group.Both groups were given postoperative lumbodorsal muscle exercises,and additionally,the control group was given conventional treatment of Celeoxib capsules orally,and the observation group was given Chinese medicine Sansheng Decoction together with Celeoxib capsules orally.Four weeks constituted one course of treatment and the treatment lasted for 3 consecutive courses.The changes of lumbago numeric rating scale(NRS)scores and Oswestry disability index(ODI)scores in the two groups were observed before and after treatment.After treatment,the clinical efficacy and safety of the two groups were evaluated.Results(1)After 3 months of treatment,the total effective rate of the observation group was 94.4%(17/18)and that of the control group was 77.8%(14/18).The intergroup comparison showed that the clinical efficacy of the observation group was significantly superior to that of the control group,and the difference was statistically significant(P<0.05).(2)After treatment for 2 weeks,2 months and 3 months,the NRS scores and ODI scores of the two groups were decreased compared with those before treatment(P<0.05),and with the prolongation of treatment time,the decrease of NRS scores and ODI scores was more obvious.The intergroup comparison showed that the NRS scores and ODI scores of the observation group were significantly lower than those of the control group after 3 months of treatment,and the difference was statistically significant(P<0.05).(3)During the treatment,there were no adverse reactions of skin hematoma,burn,infection,diarrhea,or aggravation of lumbago and leg numbness occurring in the tw

关 键 词：腰椎术后综合征 肝肾亏虚夹瘀型 三圣汤 腰背肌功能锻炼 临床疗效 

分 类 号：R274.34[医药卫生—中医骨伤科学]