MRI在可逆性胼胝体压部病变综合征中的诊断价值  

作　　者：马洁华[1] 娄斌奇 钱方达 俞瀛一 

机构地区：[1]杭州市第七人民医院,310013

出　　处：《浙江临床医学》2022年第3期423-424,共2页Zhejiang Clinical Medical Journal

摘　　要：目的研究MRI在可逆性胼胝体压部病变综合征(RESLES)中的诊断价值,进一步提高对该病的认识。方法回顾分析5例RESLES患者的影像学特征性改变及临床资料。结果5例患者中2例有头痛,3例有精神行为异常,5例患者均行MRI检查,病灶均位于胼胝体压部,病灶呈椭圆形或者回旋镖形,矢状位呈泪滴形,MRI表现:T_(1)WI呈稍低信号,T_(2)WI、FLAIR及DWI均呈高信号,ADC呈低信号。2例患者在发病7〜20 d后复查症状缓解。复查MRI表现:病灶向心性缩小,边缘模糊,T_(1)WI、T_(2)WI、FLAIR信号逐渐恢复正常,仅DWI呈稍高信号。结论可逆性胼胝体压部病变诱因复杂、临床表现多样,诊断主要依靠MRI,病灶主要累及胼胝体压部,具有可逆性,MRI可为临床诊断及预后评估提供帮助。Objective To study the magnetic resonance imaging(MRI)features of reversible splenial lesion syndrome(RESLES).Methods MRI features and clinical data of five R^ESLES patients were retrospectively analyzed.Results Two of five patients had headache.Three patients had psychological and behavioral abnormalities.All five patients underwent MRI.The oval or"boomerang sign"lesions,and teardrop abnormal signal in sagittal position were found in the splenium of the corpus callosum(SCC).MRI features included slightly hypo-intensity on T_(1)WI,hyper-intensity on T_(2)WI,FLAIR and diffusion-weighted imaging(DWI),low signal on apparent diffusion coefficient(ADC).Clinical symptoms of two patients were relieved from 7 to 20 days after the onset of disease.MRI features of reexamination showed that lesions were concentric shrinkage and fuzzy edge.And the signals of T_(1)WI,T_(2)WI and FLAIR returned to normal,only DWI showed hyper-intensity.Conclusion RESLES has complicated fundamental causes and diverse clinical manifestations,which is diagnosed as mainly dependent on MRI.MRI found a reversible lesion in the central portion of the SCC,which provides a helpful guidance in treatment and diagnosis.

关 键 词：可逆性胼胝体压部病变综合征 磁共振成像 

分 类 号：R44[医药卫生—诊断学]