Risk assessment of hepatitis E transmission through tissue allografts  

作　　者：Rafael Villalba Vicente Mirabet 

机构地区：[1]Center for Blood Transfusion,Tissues and Cells,Córdoba 14004,Spain [2]Cell and Tissue Bank,Centro de Transfusión de Valencia,Valencia 46014,Spain

出　　处：《World Journal of Gastrointestinal Pathophysiology》2022年第2期50-58,共9页世界胃肠病理生理学杂志（英文版）（电子版）

摘　　要：Hepatitis E virus(HEV)is a small non-enveloped single stranded RNA virus whose genotypes 3 and 4 have been associated with zoonotic transmission in industrialized countries.HEV infection is considered the main cause of acute hepatitis worldwide.In some cases,transfusion of blood components or organ transplantation have been reported as the source of infection.We have conducted a literature review on the risk of transmission through cell and tissue allografts.Although no case was found,measures to control this risk should be taken when donor profile(based upon geographical and behavioural data)recommended it.Issues to be considered in donor screening and tissue processing to assess and to reduce the risk of HEV transmission are approached.

关 键 词：Hepatitis E Tissue allograft Risk assessment Disease transmission Donor screening Bioburden reduction 

分 类 号：R512.6[医药卫生—内科学]