苗药验方治疗类风湿性关节炎的临床疗效  

Clinical effect observation on rheumatoid arthritis treated of prescription by traditional Miao medicine

作　　者：吴才龙 杨坚强 龙冬艳 张书优 WU Cai-long;YANG Jian-qiang;LONG Dong-yan;ZHANG Shu-you(Institute of Ethnic Medicine,Qiandongnan Miao and Dong Autonomous Prefecture,Kaili,Guizhou 556000)

机构地区：[1]黔东南苗族侗族自治州民族医药研究院,贵州凯里556000

出　　处：《中国民族医药杂志》2022年第2期1-3,共3页Journal of Medicine and Pharmacy of Chinese Minorities

基　　金：黔东南州科技计划项目:黔东南科合J字,《苗医痛痹通络方治疗类风湿性关节炎的临床疗效观察》。

摘　　要：目的:观察苗药治疗骨关节痛验方治疗类风湿性关节炎的临床疗效。方法:将40例类风湿性关节炎患者随机分为治疗组和对照组,每组20例。两组西医治疗方案相同。对照组单纯使用西药(来氟米特10 mg bid,双氯芬酸缓释胶囊50 mg bid)治疗,治疗组同时加用苗药治疗骨关节痛验方(方药组成:红禾麻、五香血藤等),1剂/d,早、中、晚分服。24周后对两组进行临床疗效观察。结果:(1)疗程结束时两组的疗效比较,治疗组总有效率为90.0%(18/20),对照组总有效率为70.0%(14/20),组间差异有统计学意义(P<0.05)。(2)不良反应比较,治疗组未出现不良反应;对照组有6例发生胃肠道不适,总发生率为30.0%(6/20)。两组不良反应总发生率比较差异有统计学意义(P<0.05)。结论:苗药配合西药治疗类风湿性关节炎疗效优于单纯使用西药治疗,在改善RA临床证候、降低不良反应发生率方面效果较为显著。Objective:To observe the clinical effect of the prescription of treat osteoarthritis form traditional Miao medicine in the treatment of rheumatoid arthritis.Methods:40 patients with rheumatoid arthritis were randomly divided into treatment group and control group,with 20 cases in each group.The western medicine treatment plan of the two groups was the same.The control group was treated with western medicine(leflunomide 10 mg bid,diclofenac sustained release capsule50 mg bid)alone,while the treatment group was additionally treated with the while the treatment group was additionally treated with the prescription of treat osteoarthritis form traditional Miao medicine(prescription composition:Honghuoma,Wuxiang Xueteng etc)1 dose daily,morning,noon and evening.After 24 weeks,the clinical efficacy of the two groups was observed and evaluated.Results:(1)Comparison of curative effect between the two groups at the end of the course of treatment showed that the total effective rate of the treatment group was 90.0%(18/20)and the total effective rate of the control group was 70.0%(14/20).The difference between groups was statistically significant(P<0.05).(2)Comparison of adverse reactions:no adverse reactions occurred in the treatment group,while 6 patients in the control group developed gastrointestinal discomfort,with a total incidence of 30.0%(6/20).The total incidence of adverse reactions between the two groups was significantly different(P<0.05).Conclusion:A prescription of treat osteoarthritis form traditional Miao medicine combined with western medicine in the treatment of RA is better than the use of western medicine alone in the treatment of rheumatoid arthritis in improving the clinical syndrome of RA,reduce the incidence of adverse reactions effect is significant.

关 键 词：苗药 类风湿性关节炎 临床观察 

分 类 号：R291.6[医药卫生—民族医学]