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作 者:Li-Cheng Lin Wen-Yen Kuan Bei-Hao Shiu Yu-Ting Wang Wan-Ru Chao Chi-Chih Wang
机构地区:[1]Department of Education,Chung Shan Medical University Hospital,Taichung 402,Taiwan [2]Department of Surgery,Chung Shan Medical University Hospital,Taichung 402,Taiwan [3]Department of Pathology,Chung Shan Medical University Hospital,Taichung 402,Taiwan [4]Division of Endoscopy,Gastroenterology and Hepatology,Department of Internal Medicine,Chung Shan Medical University Hospital,Taichung 402,Taiwan [5]School of Medicine,Chung Shan Medical University,Taichung 402,Taiwan
出 处:《World Journal of Clinical Cases》2022年第10期3156-3163,共8页世界临床病例杂志
摘 要:BACKGROUND Malignant peritoneal mesothelioma(MPM)is a rare malignancy arising in mesothelial cells in the peritoneum.It can be mistaken for many other diseases,such as peritoneal carcinomatosis and tuberculous peritonitis(TBP),because its clinical manifestations are often nonspecific.Therefore,the diagnosis of MPM is often challenging and delayed.CASE SUMMARY A 42-year-old man was referred to our hospital with lower abdominal pain for 1 wk and ascites observed under abdominal sonography.His laboratory findings revealed an isolated elevated tumor marker of carcinoma antigen 125(167.4 U/m L;normal,<35 U/m L),and contrast enhanced computed tomography showed peritoneal thickening.Thus,differential diagnoses of TBP,carcinomatosis of an unknown nature,and primary peritoneal malignancy were considered.After both esophagogastroduodenoscopy and colonoscopy produced negative findings,laparoscopic intervention was performed.The histopathological results revealed mesothelioma invasion into soft tissue composed of a papillary,tubular,single-cell arrangement of epithelioid cells.In addition,immunohistochemical staining was positive for mesothelioma markers and negative for adenocarcinoma markers.Based on the above findings,TBP was excluded,and the patient was diagnosed with MPM.CONCLUSION It is important to distinguish MPM from TBP because they have similar symptoms and blood test findings.
关 键 词:Peritoneal neoplasms Peritoneal diseases MESOTHELIOMA Malignant ascites Tuberculous peritonitis LAPAROSCOPY Case report
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