基于脑-肠轴理论探讨小儿厌食的发病机制  

A review on the pathogenesis of anorexia in children based on brain-gut axis theory

作　　者：赵志英 杨志华[2] 霍曼 崔润芝 谈慧媛 ZHAO Zhiying

机构地区：[1]甘肃中医药大学,甘肃兰州730000 [2]甘肃省中医院,甘肃兰州730050

出　　处：《中医临床研究》2022年第4期60-62,共3页Clinical Journal Of Chinese Medicine

基　　金：省自然科学基金(20JR5RA160);基于脑肠轴理论探讨运脾消食颗粒对厌食模型大鼠(脾失健运型)CCK、Ghreln含量影响的研究。

摘　　要：小儿厌食是一种以饮食不振为主要临床表现,伴或不伴消瘦的脾系疾病,在儿童生长发育的过程中很常见。近几年随着社会对小儿厌食的关注,基于对脑-肠轴理论的研究,有研究表明小儿厌食与脑肠肽的分泌异常以及胃肠动力不足关系密切,中医认为人是一个有机的整体,因此,中医理论中的整体观念可以阐释现代医学的脑-肠轴理论。从脑-肠轴学说出发,探析小儿厌食的病因病机及临床治疗,不仅有利于从整合医学理念的角度出发探析小儿厌食的发病机制,也在小儿厌食的治疗方面提出了新理念、新思路。Anorexia in children is a splenic disease characterized by lack of diet as the main clinical manifestation,with or without emaciation.It is very common in the process of children’s growth and development.In recent years,along with the social focus on infantile anorexia,based on the study of brain-gut axis theory,studies have shown that anorexia in children closely related to abnormal ghrelin secretion and insufficient gastrointestinal dynamics,TCM believes that man is an organic whole,therefore,the overall concept of traditional Chinese medicine theory can explain the brain-gut axis theory of modern medicine.Starting from the brain-gut axis theory,the analysis of the etiology,pathogenesis and clinical treatment of children’s anorexia is not only conducive to the analysis of the pathogenesis of children’s anorexia from the perspective of integrated medical concepts,but also put forward new ideas in the treatment of children’s anorexia。

关 键 词：脑-肠轴 脑肠肽 小儿厌食 

分 类 号：R272[医药卫生—中医儿科学]