A polyoxometalate based electrochemical sensor for efficient detection of L-cysteine  

作　　者：Ming-Yue Chu Jia Jiao Wei Zhu Xin Yang Ting-Ting Yu Gui-Xin Yang Hui-Yuan Ma 

机构地区：[1]School of Material Science and Chemical Engineering,Harbin University of Science and Technology,Harbin,150040,China [2]College of Chemical Engineering,Harbin Institute of Petroleum,Harbin,150028,China

出　　处：《Tungsten》2022年第2期138-148,共11页钨科技（英文）

基　　金：financially supported by the Natural Science Foundation of Heilongjiang Province (Grant No. LH2019B009)

摘　　要：L-cysteine(L-cys),as an important sulfur-containing amino acid,plays an indispensable role in biological systems.Too low and excessively high ratio of L-cys will cause harm to the function of human organs.Therefore,it is very necessary to develop efficient methods to detect it in multifarious samples.This paper has built an electrochemical sensor by combining Keggin-type polyoxometalate(PMo9V3)and cobalt tetrasulfonate(Ⅱ)phthalocyanine(CoTsPc)on indium tin oxide electrodes using the layer-level self-assembly technology for efficiently detection of L-cys.The assembly process and surface morphology of the modified electrode was characterized by ultraviolet–visible spectroscopy,X-ray photoelectron spectroscopy,scanning electron microscope,and atomic force microscopy.The conditions of electro-catalysed oxidation of L-cys were optimized by cyclic voltammetry,and the kinetic electrochemical parameters were also evaluated by electrochemical impedance spectra.Furthermore,the sensing performance of the modified electrode was explored using amperometry.The proposed electrochemical L-cys sensor was found to have superior sensing performance with a range of linear response of 2.5×10^(−7) to 1.7×10^(−4) mol·L^(−1) and 1.7×10^(−4) to 39.5×10^(−4) mol·L^(−1),the detection limit of 1.0×10^(−7) mol·L^(−1)(signal/noise=3),and satisfactory anti-interference ability.Consequently,the fabricated sensor has the potential to be applied in laboratory practices for L-cys deterimination in commercial drinks.

关 键 词：L-CYSTEINE Phosphomolybadate Cobalt(II)tetrasulfonate phthalocyanine Electrochemical sensor 

分 类 号：TS27[轻工技术与工程—农产品加工及贮藏工程] O657.1[轻工技术与工程—食品科学与工程] TP212.2[理学—分析化学]