TORCH抗体检测在优生优育检查中的临床价值  

Clinical Value of TORCH Antibody Detection in Prenatal and Postnatal Care Examination

作　　者：李晓梅 LI Xiaomei(Department of Physical Examination,Dezhou Center for Disease Control and Prevention,Dezhou Shandong 253000,China)

机构地区：[1]德州市疾病预防控制中心体检科,山东德州253000

出　　处：《中国卫生标准管理》2022年第6期13-16,共4页China Health Standard Management

基　　金：山东省中医药科技项目(2020M179)。

摘　　要：目的探究与分析TORCH抗体检测在优生优育检查中的临床价值。方法选取本单位原德州市计划生育指导中心2015年1月—2016年1月收治的经过TORCH[弓形虫(toxoplasmagondi,TOXO)、风疹病毒(rubella,RUB)、巨细胞病毒(cytomegalovirus,CMV)、单纯疱疹病(herpes simplex virus,HSV)]抗体检测的67例不孕不育妇女作为观察组,102例优生优育妇女作为对照组。对两组妇女TORCH抗体检测临床资料进行分析,同时统计观察组不同病原体女性无异常妊娠史、有异常妊娠史比例,观察组的TORCH抗体检测结果在不同年龄层中的分布情况。结果两组妇女TORCH抗体检测结果中弓形虫IgM抗体(toxoplasmagondi-immunoglobulin M,TOX-IgM)及单纯疱疹病(herpes simplex virus-immunoglobulin M,HSV-IgM)的检出率相比差异无统计学意义(P>0.05)。观察组与对照组相比TORCH抗体检测结果中风疹病毒(rubella-immunoglobulin M,RV-IgM)及巨细胞病毒(cytomegalovirus-immunoglobulin M,CMV-IgM)的检出率较高,差异有统计学意义(P<0.05)。在观察组TORCH抗体检测结果阳性妇女当中,有异常妊娠史者的比例均高于无异常妊娠史者。观察组<30岁与≥30岁的妇女中TORCH抗体检测结果为TOX-IgM、RV-IgM、CMVIgM、HSV-IgM的比例差异无统计学意义(P>0.05)。结论TORCH抗体在异常妊娠妇女中呈现出了较高的比例,与优生优育妇女存在明显的差异性,可见TORCH抗体检测在优生优育的检查中具有较高的应用价值。Objective To explore and analyze the clinical value of TORCH antibody detection in eugenics examination.Methods A total of 67 infertile women who had undergone toxoplasma,rubella virus,cytomegalovirus,herpes simplex disease(TORCH)antibody test were selected as observation.group,102 eugenic and postnatal women were selected as the control group from January 2015 to January 2016.The clinical data of TORCH antibody detection in the two groups of women was analyzed,and the proportion of women with different pathogens in the observation group without abnormal pregnancy history and with abnormal pregnancy history was counted,and the distribution of TORCH antibody detection results in different age groups in the observation group.Results There was no significant difference in the detection rate of Toxoplasma gondii IgM antibody and herpes simplex disease in the TORCH antibody test results in the two groups of women(P>0.05).Compared with the control group,the TORCH antibody detection results showed a higher detection rate of rubella virus and cytomegalovirus in the observation group,and the difference was statistically significant(P<0.05).Among the women with positive TORCH antibody test results in the observation group,the proportions of those with a history of abnormal pregnancy were higher than those without a history of abnormal pregnancy,and the difference was statistically significant(P<0.05).There was no significant difference in the proportions of TOX-IgM,RV-IgM,CMV-IgM and HSV-IgM in the TORCH antibody test results between women aged<30 and≥30 years old in the observation group(P>0.05).Conclusion TORCH antibody shows a high proportion in abnormal pregnancy women,and there is a significant difference with prenatal and postnatal women.It can be seen that TORCH antibody detection has high application value in the examination of prenatal and postnatal care.

关 键 词：TORCH抗体检测 优生优育 检查 异常妊娠 人口质量 妊娠结局 

分 类 号：R446[医药卫生—诊断学]