3D-CPA联合CDFI对妊高症孕妇胎盘功能评定的可行性研究  

Feasibility study of 3D-CPA combined with CDFI for assessment of placental function in pregnant women with gestational hypertension

作　　者：丁学谨 高洁 唐春莲 DING Xue-jin;GAO Jie;TANG Chun-lian(Wuhan Wuchang Hospital,Wuhan 430081,China)

机构地区：[1]武汉市武昌医院,武汉430081

出　　处：《医疗卫生装备》2022年第3期60-65,共6页Chinese Medical Equipment Journal

基　　金：湖北省科技计划项目(2017CFA069)。

摘　　要：目的:探讨三维彩色能量成像(three-dimensional color power angiographic,3D-CPA)联合彩色多普勒血流成像(color Doppler flow imaging,CDFI)对妊高症孕妇胎盘功能评定的可行性。方法:回顾性收集某院2018年1月至2020年6月期间就诊的孕周为30~42周的180例孕妇的临床资料,根据是否存在妊高症将180例孕妇分为实验组(100例)和对照组(80例),并根据实验组孕妇临床表现严重程度分为轻度子痫前期组(A组,78例)和重度子痫前期组(B组,22例),实验组和对照组均行3D-CPA联合CDFI检查,记录胎儿脐动脉、胎儿大脑中动脉、子宫动脉的收缩末期峰值/舒张末期峰值(systolic/diastolic,S/D)、搏动指数(pulsatile index,PI)、阻力指数(resistance index,RI)及胎盘血管化指数(vascularization index,VI)、血流指数(flow index,FI)和血管化血流指数(vascularization-flow index,VFI)值。采用SPSS 18.0软件进行统计学分析。结果:B组孕妇年龄明显大于对照组及A组(P均<0.05),A组孕妇年龄大于对照组(P<0.05);实验组和对照组孕妇的孕次、产次无明显差异(P均>0.05);B组孕妇胎儿脐动脉血流参数S/D、PI、RI值明显高于对照组及A组(P均<0.05);B组、A组孕妇子宫动脉血流参数S/D、PI、RI值均高于对照组(P均<0.05);B组、A组胎盘三维能量指数VI、FI、VFI值均明显低于对照组(P均<0.05);对照组、实验组孕37周+孕妇血流参数S/D、PI、RI值均低于孕30~37周孕妇(P均<0.05),实验组孕37周+血流参数S/D、PI、RI值均低于对照组孕37周+孕妇(P均<0.05)。结论:3D-CPA联合CDFI可对子宫动脉、脐动脉以及胎儿大脑中动脉相关血流参数及胎盘三维能量指数进行量化分析,在妊高症孕妇胎盘功能评估方面具有重要意义,可为临床医师评估孕妇胎盘功能提供参考。Objective To investigate the feasibility of three-dimensional color power angio graphic(3D-CPA)combined with color Doppler flow imaging(CDFI)in the evaluation of placental function in patients with gestational hypertension.Methods Clinical data were retrospectively collected from 180 pregnant women with gestational age of 30 to 42 weeks who visited some hospital between January 2018 and June 2020.The 180 pregnant women were divided into an experimental group(100 cases)and a control group(80 cases)according to the presence of gestational hypertension,and the ones in the experimental group were enrolled into a mild preeclampsia sub-group(sub-group A,78 cases)and a severe preeclampsia sub-group(sub-group B,22 cases)according to the severity of clinical manifestations.3D-CPA combined with CDFI was performed in both the experimental and control groups to record the end-systolic/diastolic(S/D),pulsatile index(PI),resistance index(RI),vascularization index(VI),flow index(FI)and vascularization-flow index(VFI)values of fetal umbilical artery,fetal middle cerebral artery and uterine artery.SPSS 18.0 software was used for statistical analysis.Results Maternal age was significantly higher in sub-group B than in the control group and sub-group A(P<0.05),and in sub-group A than in the control group(P<0.05);there were no significant differences in the gestation and delivery times between the experimental and control groups(P>0.05);the values of S/D,PI and RI of fetal umbilical artery blood flow parameters were significantly higher in sub-group B than in the control group and sub-group A(P<0.05);the values of S/D,PI and RI of uterine artery blood flow parameters were higher in sub-group B and sub-group A than in the control group(P<0.05);the values of placental 3D energy indices VI,FI,and VFI in sub-group B and A were significantly lower than those in the control group(P<0.05);the values of blood flow parameters S/D,PI,and RI in the control and experimental groups were lower than those in pregnant women at 30 to 37 weeks of ges

关 键 词：妊高症 三维彩色能量成像 胎盘三维能量灌注 彩色多普勒血流成像 胎盘功能 血流动力学 

分 类 号：R318[医药卫生—生物医学工程] R445.1[医药卫生—基础医学]