外泌体微小RNA与心血管疾病研究的进展  

Research progress of exosome microRNA and cardiovascular disease

作　　者：毕鑫[1] 原玥 李悦[1] BI Xin;YUAN Yue;LI Yue(Department of Cardiology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院心血管内科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2022年第2期237-241,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

基　　金：国家自然科学基金项目(81830012)。

摘　　要：心血管疾病(CVD)是导致患者死亡的主要原因,早期诊断和治疗靶点的缺乏是CVD防治不佳的主要因素。大量研究证实,外泌体微小RNA(miRNA)与冠心病、心房颤动及心衰等多种CVD密切相关,在CVD的诊断和治疗方面具有巨大潜力。本文就外泌体miRNA与CVD的相关研究作一综述,旨在为外泌体miRNA在CVD早期诊断及防治中的应用提供依据。Cardiovascular disease(CVD)is a main cause of death in patients,and lack of early diagnosis and therapeutic targets are main factors for poor prevention and treatment of CVD.A large number of studies have confirmed that exosome miRNA is closely related to various CVDs such as coronary heart disease,atrial fibrillation and heart failure etc.,and it possesses great potential in diagnosis and treatment of CVD.The present article makes a review on related researches of exosome miRNA and CVD,aiming at providing a basis for application of exosome miRNA in early diagnosis,prevention and treatment of CVD.

关 键 词：心血管疾病 微RNAS 外泌体 

分 类 号：R54[医药卫生—心血管疾病]