医用回旋加速器的临床应用综述  

Overview of Clinical Application of Medical Cyclotron

作　　者：何正中 李宁[1] 廖光星 肖国有[1] HE Zhengzhong;LI Ning;LIAO Guangxing;XIAO Guoyou(Department of Nuclear Medicine(Guangxi Clinical Key Specialty),Guangxi Medical University Affiliated Tumor Hospital,Nanning Guangxi 530021,China)

机构地区：[1]广西医科大学附属肿瘤医院核医学科(广西临床重点建设专科),广西南宁530021

出　　处：《中国医疗设备》2022年第4期149-153,共5页China Medical Devices

基　　金：广西科技计划项目重点研发计划(桂科AB19110015);广西壮族自治区卫生健康委员会自筹经费课题(Z20190559,Z20190595,Z20190632);2020年广西医科大学教育教学改革立项项目(2020XJGB16,2020XJGKT07)。

摘　　要：医用回旋加速器是医用放射性核素的主要来源,用于制备PET/CT显像所需的正电子核素,能制备氟-18(^(18)F)、碳-11(^(11)C)、氮-13(^(13)N)、铜-64(^(64)Cu)、锆-89(^(89)Zr)、碘-124(^(124)I)等。医用回旋加速器的普及不仅满足了临床对放射性药物的需求,也推动了新型正电子分子探针的研制和使用,进而促进了核医学的诊疗应用和研究。本文从医用回旋加速器的原理及其临床应用等方面进行综述,以期为核医学工作者进行相关临床应用及新型分子探针研制等科研工作提供更多的选择。Medical cyclotron is used to produce ^(18)F,^(11)C,^(13)N,^(64)Cu,^(89)Zr,^(124)I,etc.,which is the main source of medical radionuclides.The popularization of cyclotron not only meets the clinical demand for radiopharmaceuticals,but also promotes the development and application of new positron molecular probes,and further promotes the application and research of nuclear medicine.In this paper,the principle and clinical application of cyclotrons were reviewed in order to provide more choices for nuclear medical workers in related clinical applications,scientific research and development of new molecular probes.

关 键 词：医用回旋加速器 正电子核素 核医学 PET/CT 核素制备 

分 类 号：R445.5[医药卫生—影像医学与核医学]