经直肠超声造影联合剪切波弹性成像诊断前列腺良恶性病变的价值  

Value of transrectal contrast-enhanced ultrasound combined with shear wave elastography in the differential diagnosis of benign and malignant prostatic lesions

作　　者：王南[1] 叶新华[2] 刘辉[1] 王丽杰 朱成涛 谢晴晴 刘丽[1] 王亮 WANG Nan;YE Xinhua;LIU Hui;WANG Lijie;ZHU Chengtao;XIE Qingqing;LIU Li;WANG Liang(Department of Ultrasound,The Affiliated Suqian First People's Hospital of Nanjing Medical University,Suqian 223800,China;Department of Ultrasound,The First Affiliated Hospital With Nanjing Medical University,Nanjing 210029,China;Department of Ultrasound,Nanjing Drum Tower Hospital,Nanjing 210005,China)

机构地区：[1]南京医科大学附属宿迁第一人民医院超声医学科,江苏宿迁223800 [2]南京医科大学第一附属医院超声诊断科,江苏南京210029 [3]南京市鼓楼医院超声医学科,江苏南京210005

出　　处：《分子影像学杂志》2022年第2期244-247,共4页Journal of Molecular Imaging

基　　金：江苏省自然科学基金青年基金(SBK202004300)。

摘　　要：目的分析经直肠超声造影(CETRUS)联合剪切波弹性成像鉴别诊断前列腺良恶性病变的价值。方法选取2020年5月≈2021年12月我院收治的102例前列腺疾病患者,以经直肠超声(TRUS)引导前列腺穿刺活检为金标准,将其分为前列腺癌组(n=37)和前列腺增生组(n=65),对所有患者进行经直肠超声造影联合剪切波弹性成像检查,比较两组患者的E;值和E;值,比较不同方法的诊断准确度。结果前列腺癌组患者E;、E;值明显高于前列腺增生组患者,差异有统计学意义(P<0.05);CETRUS联合剪切波弹性成像诊断前列腺良恶性病变的敏感度、特异性、准确率明显高于单一CETRUS检查,单一技术诊断(81.08%、80.00%、80.39%vs 56.76%、64.62%、61.76%,P<0.05);CETRUS联合剪切波弹性成像的曲线下面积为0.748(95%CI:0.534~0.760),大于单一CETRUS曲线下面积0.685(95%CI:0626~0851)。结论 经直肠超声造影联合剪切波弹性成像可通过杨氏模量值来反应组织的硬度,进而对前列腺良恶性病变进行诊断,在临床上具有一定的应用价值。Objective To analyze the value of transrectal contrast-enhanced ultrasound(CETRUS) combined with shear wave elastography in the differential diagnosis of benign and malignant prostate lesions.Methods A total of 102 patients with prostate diseases admitted to our hospital from May 2020 to December 2021 were selected,and divided into prostate cancer group(n=37) divided into prostate cancer group(n=37).All patients underwent transrectal contrast-enhanced ultrasound combined with shear wave elastography.E;value and E;were compared between the two groups,and the diagnostic accuracy of different methods was compared.Results The E;value and E;in prostate cancer group were significantly higher than those in benign prostatic hyperplasia group(P<0.05).The sensitivity,specificity and accuracy of CETRUS combined with shear wave elastography in diagnosing benign and malignant prostate lesions were significantly higher than those of CETRUS alone(81.08%、80.00%、80.39% vs 56.76%、64.62%、61.76%,P<0.05).The area under the curve of CETRUS combined with shear wave elastography was 0.748(95%CI:0.534-0.760),which was larger than that of CETRUS alone 0.685(95%CI:0.266-0.851).Conclusion Transrectal contrast-enhanced ultrasound combined with shear-wave elastography can reflect tissue hardness through Young’s modulus value,and then diagnose benign and malignant prostate lesions,which has certain clinical value.

关 键 词：经直肠超声 剪切波弹性成像 前列腺 恶性病变 价值 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]