老年慢性心力衰竭患者合并贫血情况及其影响因素分析  

Analysis of anemia in elderly patients with chronic heart failure and its influencing factors

作　　者：成昌盛[1] 蔡文娟[1] 曹慧玲[2] CHENG Changsheng;CAI Wenjuan;CAO Huiling(Outpatient and Emergency Center,Jiangsu Province Hospital of Traditional Chinese Medicine,Jiangsu Province,Nanjing 210029,China;Department of Laboratory,Jiangsu Province Hospital of Traditional Chinese Medicine,Jiangsu Province,Nanjing 210029,China)

机构地区：[1]江苏省中医院门急诊中心,江苏南京210029 [2]江苏省中医院检验科,江苏南京210029

出　　处：《中国医药导报》2022年第8期60-63,共4页China Medical Herald

基　　金：国家自然科学基金资助项目(81703830)。

摘　　要：目的探讨老年慢性心力衰竭患者合并贫血情况及其影响因素。方法选择2018年3月至9月江苏省中医院诊治的1275例老年慢性心力衰竭患者,根据血红蛋白<120 g/L(男性)或<110 g/L(女性)将其分为非贫血组(946例)和贫血组(329例),比较两组一般资料及临床数据,分析老年慢性心力衰竭患者合并贫血的影响因素。结果共329例(25.8%)老年慢性心力衰竭患者并发贫血,其中轻度贫血167例,中度贫血98例,重度贫血64例;贫血原因为缺铁性贫血241例,肾性贫血34例,巨幼细胞性贫血27例,其他原因贫血27例。贫血组年龄、心力衰竭病程、纽约心脏学会(NYHA)分级为Ⅲ~Ⅳ级占比、合并慢性肾病占比、1年内因心力衰竭住院次数及住院天数均高于非贫血组,差异有统计学意义(P<0.05)。多因素分析结果显示,文化程度、白蛋白水平、心力衰竭病程、NYHA分级是老年慢性心力衰竭患者发生贫血的影响因素(P<0.05)。结论老年慢性心力衰竭患者合并贫血可能与其文化程度、白蛋白水平、心力衰竭病程、NYHA分级有关。Objective To investigate the anemia and its influencing factors in elderly patients with chronic heart failure.Methods A total of 1275 elderly patients with chronic heart failure diagnosed and treated in Jiangsu Province Hospital of Traditional Chinese Medicine from March to September 2018 were selected and divided into non-anemia group(946 cases)and anemia group(329 cases)according to hemoglobin<120 g/L(male)or<110 g/L(female).The general data and clinical data of the two groups were compared to analyze the influencing factors of anemia in elderly patients with chronic heart failure.Results A total of 329(25.8%)elderly patients with chronic heart failure complicated with anemia,including 167 cases of mild anemia,98 cases of moderate anemia,64 cases of severe anemia.The causes of anemia were iron deficiency anemia in 241 cases,renal anemia in 34 cases,megaloblastic anemia in 27 cases,and anemia of other causes in 27 cases.Age,course of heart failure,proportion of New York Heart Association(NYHA)grade Ⅲ to Ⅳ,proportion of complicated chronic kidney disease,average number of hospitalization,and length of hospitalization for heart failure within one year in anemia group were higher than those in non-anemia group,the differences were statistically significant(P<0.05).The results of multivariate analysis showed that education level,albumin level,heart failure course,and NYHA grade were the influencing factors of anemia in elderly patients with chronic heart failure(P<0.05).Conclusion Anemia in elderly patients with chronic heart failure may be related to their educational level,albumin level,heart failure course,and NYHA grade.

关 键 词：老年 慢性心力衰竭 贫血 影响因素 

分 类 号：R541.6[医药卫生—心血管疾病]