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作 者:李佳卓[1] 王玉丹 隋艳波[1] 张鸿婷[1] 邹国良[1] 郭丹丹[1] LI Jiazhuo;WANG Yudan;SUI Yanbo;ZHANG Hongting;ZOU Guoliang;GUO Dandan(Heilongjiang University of Chinese Medicine,Heilongjiang Province,Harbin 150040,China)
出 处:《中国医药导报》2022年第6期118-122,146,共6页China Medical Herald
基 金:国家自然科学基金资助项目(81904107);黑龙江中医药大学科研基金项目(201833);黑龙江省教育厅科学技术研究项目(12541738);黑龙江省中医药科研项目(ZHY2020-148);黑龙江省哈尔滨市应用技术研究与开发项目(2017RAQXJ208)。
摘 要:目的评价益气温阳、活血利水法治疗慢性心力衰竭系统评价的方法学质量,并对系统评价纳入试验的结局指标进行评估。方法计算机检索中国知网、万方、维普、PubMed和Cochrane Library数据库,搜索益气温阳、活血利水法治疗慢性心力衰竭的系统评价,检索时限均为建库至2020年12月。由两名研究人员独立筛选和提取资料,产生异议时由第3位人员决定,然后用AMSTAR2量表对纳入文献的方法学质量进行评价,用GRADE分级对纳入文献的证据质量进行评价。结果最终纳入14个系统评价,用AMSTAR2量表评价纳入研究的方法学质量,有7个条目报告较为完整,5个条目未报告,总体质量偏低。用GRADE评价结局指标,结局指标证据分级有中等质量、低质量和极低质量。结论益气温阳、活血利水法可有效治疗慢性心力衰竭,但目前所检索到的系统评价存在方法学质量较低、证据质量不高等问题。今后应进行高质量研究,另外对系统评价的撰写应做到规范客观。Objective To evaluate methodological quality of systematic evaluation of invigorating qi and warming yang,promoting blood circulation and inducing diuresis in treating chronic heart failure,and evaluate the outcome indicators included in the systematic review.Methods The databases of CNKI,Wanfang,VIP,PubMed and Cochrane Library were searched by computer.The systematic evaluation of invigorating qi and warming yang,promoting blood circulation and inducing diuresis in treating chronic heart failure was searched.The retrieval time limit was from the establishment of the database to December 2020.Data was independently screened and extracted by two researchers,in case of any objection,it shall be decided by the third person,then the methodological quality of the included literature was evaluated with AMSTAR2 scale,GRADE classification was used to evaluate the quality of evidence included in the literature.Results Finally,14 systematic evaluations were included,the methodological quality of the included studies was evaluated with AMSTAR2 scale,seven items were reported completely,five items were not reported,and the overall quality was low.GRADE was used to evaluate the outcome indicators,the evidence grades of outcome indicators were medium quality,low quality and very low quality.Conclusion Invigorating qi and warming yang,promoting blood circulation and inducing diuresis can effectively treat chronic heart failure.However,there are some problems in the retrieved system evaluation,such as low quality of methodology and low quality of evidence.High quality research should be carried out in the future.In addition,the writing of system evaluation should be standardized and objective.
关 键 词:益气温阳 活血利水 慢性心力衰竭 系统评价再评价 AMSTAR2 GRADE
分 类 号:R256.2[医药卫生—中医内科学]
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