2009—2019年秦皇岛市手足口病监测分析  

Monitoring and analysis of hand-foot-mouth disease in Qinhuangdao City from 2009 to 2019

作　　者：陶旭[1] 史明坤[1] 罗永松[1] 郑立新[1] 郭建伟 张少东 TAO Xu;SHI Ming-kun;LUO Yong-song;ZHENG Li-xin;GUO Jian-wei;ZHANG Shao-dong(Qinhuangdao Center for Disease Control and Prevention,Hebei 066000,China)

机构地区：[1]秦皇岛市疾病预防控制中心,河北066000

出　　处：《医学动物防制》2022年第2期156-159,F0003,共5页Journal of Medical Pest Control

基　　金：秦皇岛市级科学技术研究与发展计划——重大突发公共卫生事件风险评估模型研究(202003B027)。

摘　　要：目的分析2009—2019年秦皇岛市手足口病流行特征,为今后制定防控策略提供科学依据。方法采用描述流行病学方法对2009—2019年"中国疾病预防控制信息系统"中的传染病报告信息管理系统报告的秦皇岛市手足口病病例和手足口病实验室监测系统中病原学检测结果进行分析。结果2009—2019年秦皇岛市共报告手足口病病例25336例,年均报告发病率75.30/10万。流行曲线主要呈单峰分布,发病集中在6—8月,个别年份在10月或11月病例数会略有上升。报告发病率高和重症率高的地区分布不同。手足口病发病主要集中在6岁以下儿童,各年龄组报告发病率及重症率差异均有统计学意义(χ^(2)=2731.034,P<0.01;χ^(2)=13.361,P=0.02)。1~<4岁儿童报告发病率最高,重症及死亡病例也主要集中在1~<4岁儿童。男女比为1.50∶1。男女年均报告发病率分别为90.70/10万和61.86/10万,差异有统计学意义(χ^(2)=902.703,P<0.01)。近年来其他肠道病毒逐渐增多,但EV 71型仍是重症病例和死亡病例的优势毒株。结论秦皇岛市手足口病呈现明显的时间、人群,及一定的地区分布规律,应进一步关注手足口病病原谱尤其是其他肠道病毒的分型,同时加强重点人群、地区的防控。Objective Analyze the epidemiological characteristics of hand-foot-mouth disease(HFMD)in Qinhuangdao City from 2009 to 2019,and to provide a scientific basis for formulating prevention and control strategies in the future.Methods A descriptive epidemiological method was used to analyze the HFMD cases reported in the Infectious Disease Report Information Management System of"the Chinese Disease Prevention and Control Information System"and the pathogen detection results in the laboratory surveillance system of HFMD in Qinhuangdao from 2009 to 2019.Results In Qinhuangdao,a total of 25336 cases of HFMD were reported from 2009 to 2019,with an average annual reported incidence rate of 75.30/100000.The epidemic curve mainly showed a single peak distribution,the incidence was concentrated in June to August,and the number of cases increased slightly in October or November in individual years.The distribution of areas reporting high incidence and high rates of the severe disease varies.The incidence rate of HFMD mainly concentrated in children under 6 years of age.There were significant differences in reported morbidity and severity rates among 6 age groups under 6 years of age(χ^(2)=2731.034,P<0.01;χ^(2)=13.361,P=0.02).The incidence rate of children aged 1-<4 was the highest,and the number of deaths and deaths was mainly concentrated in children aged 1-<4.The ratio of male to female was 1.50∶1.The incidence rate of male and female reported in each year was 90.70/100000 and 61.86/100000,respectively,and the difference was statistically significant(χ^(2)=902.703,P<0.01).In recent years,other enteroviruses had increased gradually,but EV 71 was still the dominant strain causing severe cases and death cases.Conclusion HFMD in Qinhuangdao City shows a clear temporal,population,and certain regional distribution pattern.It is necessary to pay more attention to the pathogen spectrum of HFMD,especially the typing of other enteroviruses,and strengthen the prevention and control of key populations and regions.

关 键 词：手足口病 流行特征 病原监测 分析 

分 类 号：R512.5[医药卫生—内科学]