3.0T磁共振弥散加权序列对原发性肝癌TACE术后疗效评估  

Evaluation of 3.0T MR diffusion weighted imaging sequence in the postoperative efficacy of TACE for primary liver cancer

作　　者：吴杰 肖安岭[1] 李卫[2] 陈雷[3] 韩明锋[4] 李秀勇[5] WU Jie;XIAO Anling;LI Wei;CHEN Lei;HAN Mingfeng;LI Xiuyong(Department of MRI,Fuyang Second People's Hospital,Fuyang,Anhui 236015,China;Department of Infectious Disease,Fuyang Second People's Hospital,Fuyang,Anhui 236015,China;Department of Radiology,Fuyang Second People's Hospital,Fuyang,Anhui 236015,China;Department of Respiratory,Fuyang Second People's Hospital,Fuyang,Anhui 236015,China;Department of Nephrology,Fuyang Second People's Hospital,Fuyang,Anhui 236015,China)

机构地区：[1]阜阳市第二人民医院MRI室,安徽阜阳236015 [2]阜阳市第二人民医院感染科,安徽阜阳236015 [3]阜阳市第二人民医院放射科,安徽阜阳236015 [4]阜阳市第二人民医院呼吸科,安徽阜阳236015 [5]阜阳市第二人民医院肾内科,安徽阜阳236015

出　　处：《影像研究与医学应用》2022年第6期37-39,共3页Journal of Imaging Research and Medical Applications

基　　金：阜阳市卫健委科研立项课题(FY-2019-073)。

摘　　要：目的:探讨磁共振弥散加权成像(diffusion weighted imaging,DWI)序列对原发性肝癌介入术后疗效评估,及早指导临床治疗,改善患者预后,提高生存率。方法:选取阜阳市第二人民医院2018年6月—2021年8月期间收治的40例行经导管动脉栓塞化疗(transcatheter arterial chemo embolization,TACE)的原发性肝癌患者为研究对象,术后均行MRI动态增强扫描和DWI序列扫描,采用欧洲肝脏研究协会制定标准评估肿瘤活性,回顾性分析肿瘤坏死组织及残留组织的ADC值,比较两者差异是否有统计学意义。结果:3.0T磁共振弥散加权序列与动态增强序列对原发性肝癌TACE术后活性的诊断符合率比较,差异有统计学意义(P<0.05);肿瘤组织的平均ADC值为(1.08±0.12)×10^(-3) m m^(2)/s,介入术后肿瘤组织的平均ADC值为(1.23±0.15)×10^(-3) m m^(2)/s,两者之间差异有统计学意义(P<0.05)。结论:磁共振DWI序列可以对肝癌TACE术后疗效进行评估,为临床治疗提供依据。Objective To evaluate the efficacy of magnetic resonance diffusion weighted imaging(DWI) sequence after interventional surgery for primary liver cancer,guide clinical treatment as soon as possible,improve the prognosis and improve the survival rate.Methods 40 patients with primary liver cancer treated by transcatheter arterial chemoembolization(TACE) in Fuyang Second People’s Hospital from June 2018 to August 2021 were selected as the research object.Dynamic contrast-enhanced magnetic resonance scan and DWI sequence were performed after operation.The tumor activity and compliance score were evaluated according to the standards formulated by the European Association for the Study of the Liver whether the ADC value of tumor necrotic tissue and residual tissue was statistically significant.Results There was significant difference in the diagnostic coincidence rate between 3.0T MR diffusion weighted imaging sequence and dynamic contrast-enhanced sequence in the diagnosis in the activity of primary liver cancer after TACE(P< 0.05).There was significant difference between the average ADC value[(1.08±0.12)×10^(-3)mm^(2)/s]of tumor tissue and the average ADC value[(1.23±0.15)×10^(-3)mm^(2)/s]of tumor tissue after interventional surgery(P< 0.05).Conclusion Magnetic resonance DWI sequence can evaluate the curative effect of TACE for liver cancer and provide basis for clinical treatment.

关 键 词：弥散加权成像 肝癌 介入治疗 

分 类 号：R445[医药卫生—影像医学与核医学]