脑心清片对动脉粥样硬化患者血脂和血流动力学的影响  

Effect of Naoxinqing on Blood Lipids and Hemodynamics in Patients with Atherosclerosis

作　　者：樊慧珠 FAN Huizhu(Department of Pharmacy,Zhengzhou Seventh People's Hospital,Henan Province,Zhengzhou 450000,China)

机构地区：[1]郑州市第七人民医院药学部,河南郑州450000

出　　处：《光明中医》2022年第6期944-947,共4页GUANGMING JOURNAL OF CHINESE MEDICINE

摘　　要：目的 观察脑心清对动脉粥样硬化者血脂和血流动力学的影响,分析脑心清在动脉粥样硬化治疗中的价值。方法 选取郑州市第七人民医院2019年1月—2020年8月住院治疗的动脉粥样硬化者为研究对象,随机选取260例患者,按就诊单双号分为观察组130例和对照组130例,对照组接受西医常规治疗,观察组在常规治疗同时联合使用脑心清,对比分析血脂、血流动力学、血流变学指标变化情况。结果 观察组、对照组治疗后TC、TG、LDL-C、PI、RI明显下降,HDL-C、大脑中动脉Vs、椎动脉Vs明显升高,与本组治疗前比较,差异具有统计学意义(P <0.05);观察组治疗后TC、TG、LDL-C、PI、RI下降幅度大于对照组,HDL-C大脑中动脉Vs、椎动脉Vs升高幅度大于对照组,差异具有统计学意义(P <0.05)。结论 脑心清能改善动脉粥样硬化患者血脂、血流变及血流动力,有利于改善血液高凝状态,预防血栓形成。Objective To observe the effect of Naoxinqing on blood lipids and hemodynamics in patients with atherosclerosis,and to analyze the value of Naoxinqing in the treatment of atherosclerosis.Methods The patients with atherosclerosis who were hospitalized in Zhengzhou Seventh People’s Hospital between January 2019 and August 2020 were selected as the research objects.260 patients were randomly selected and divided into observation group of 130 cases and control group of 130 according to the number of treatment.The control group received conventional western medicine treatment,and the observation group used Naoxinqing in combination with conventional treatment.Changes in blood lipids,hemodynamics,and hemorheology were compared and analyzed.Results TC,TG,LDL-C,PI,RI decreased significantly in the observation group and control group after treatment,and HDL-C,middle cerebral artery Vs,and vertebral artery Vs increased significantly.Compared with this group before treatment,the difference was statistically significant( P < 0.05).After treatment,the decrease of TC,TG,LDL-C,PI and RI in the observation group was greater than that in the control group,the increase of HDL-C middle cerebral artery VS and vertebral artery Vs was greater than that in the control group,and the difference was statistically significant( P <0.05).Conclusion Naoxinqing can improve blood lipids,blood rheology and blood fluidity in patients with atherosclerosis,help improve blood hypercoagulability and prevent thrombosis.

关 键 词：中风 动脉粥样硬化 脑心清片 血流变 血流动力学 

分 类 号：R259[医药卫生—中西医结合]