The influence of alternating cyclic dynamic loads with different low frequencies on the bio-corrosion behaviors of AZ31B magnesium alloy in vitro  

作　　者：Linyuan Han Zhenwei Zhang Jianwei Dai Xuan Li Jing Bai Zhihai Huang Chao Guo Feng Xue Chenglin Chu 

机构地区：[1]School of Materials Science and Engineering,Southeast University,Nanjing,211189,Jiangsu,China [2]Jiangsu Key Laboratory for Advanced Metallic Materials,Southeast University,Nanjing,211189,Jiangsu,China [3]School of Materials Engineering,Nanjing Institute of Technology,Nanjing,211189,Jiangsu,China [4]Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology,Nanjing,211189,China

出　　处：《Bioactive Materials》2022年第1期263-274,共12页生物活性材料（英文）

基　　金：This research was supported by the National Natural Science Foundation of China(Grant No.51771054);State Key Program of National Natural Science Foundation of China(Grant No.51631003);National Key Research and Development Program of China(Grant No.2016YFC1102402);the Open Research Fund of Jiangsu Key Laboratory for Advanced Metallic Materials(Grant No.AMM2021A01);the Opening Project of Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology(Grant No.ASMA201901);Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX20_0091);Natural Science Foundation of Jiangsu Province(BK20181020);and the Introduction of Talent Research Fund in Nanjing Institute of Technology(YKJ201705).

摘　　要：The real physiological environment of human body is complicated with different degrees and forms of dynamic loads applied to implanted medical devices due to the daily activities of the patients,which would have impacts on the degradation behaviors of magnesium alloy implants.In this work,the bio-corrosion behaviors of AZ31B magnesium alloy under alternating cyclic dynamic loads with different low frequencies(0.1-2.5 Hz)were specially investigated.It was found that the bio-degradation performances under external dynamic stressed conditions were much severer than those under unstressed conditions and static loads.The corrosion rates were generally accelerated as the rise of cyclic frequency.Hereby a numerical model for the degradation process of Mg alloy was established.The corrosion current density icorr of Mg alloy and the applied loading frequency f matches a linear relationship of ln icorr∝f,which is the result of interactions between the cyclic alternating load and corrosive environment.This work could provide a theoretical reference and an experimental basis for further researches on the biodegradation behaviors of biomedical materials under dynamic conditions.

关 键 词：Magnesium alloy BIOCORROSION FATIGUE Frequency 

分 类 号：R318[医药卫生—生物医学工程] TB3[医药卫生—基础医学]