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作 者:李双林 LI Shuanglin(Children’s Hospital of Zhengzhou University/Henan Children‘s Hospital/Zhengzhou Children’s Hospital,Henan Zhengzhou 450000,China)
机构地区:[1]郑州大学附属儿童医院/河南省儿童医院/郑州儿童医院,河南郑州450000
出 处:《中国医药导刊》2022年第3期234-237,共4页Chinese Journal of Medicinal Guide
摘 要:目的:探究祛风宣肺健脾法配合氯雷他定糖浆口服治疗小儿过敏性咳嗽风邪犯肺证的疗效。方法:选取2020年2月至2021年2月于我院就诊的92例过敏性咳嗽风邪犯肺证患儿作为研究对象,根据随机数字表法分为对照组和观察组,每组46例。对照组给予氯雷他定糖浆口服治疗,观察组在对照组治疗基础上给予祛风宣肺健脾法治疗,对比分析两组患儿疗效、咳嗽症状评分、临床指标恢复时间及血清炎性因子水平。结果:观察组治疗显效率为95.65%(44/46),高于对照组的82.61%(38/46)(P<0.05)。治疗后,,观察组患儿咳嗽症状评分低于对照组(P<0.05)。观察组患儿咳嗽缓解时间、咳嗽消失时间、肺啰音消失时间均短于对照组(P<0.05)。治疗后,观察组患儿血清白介素-4(IL-4)、肿瘤坏死因子-α(TNF-α)、白介素-5(IL-5)、白介素-6(IL-6)表达水平低于对照组(P<0.05)。结论:采用祛风宣肺健脾法配合氯雷他定糖浆口服治疗小儿过敏性咳嗽风邪犯肺证,有利于提高治疗效果,减轻患者咳嗽症状,缩减临床恢复时间,降低炎性因子水平。Objective:To explore the efficacy of dispelling pathogenic wind,dispersing lung qi and strengthening spleen therapy combined with oral loratadine syrup in the treatment of wind evil invading lung syndrome of atopic cough in children.Methods:92 atopic cough children with the syndrome of wind evil invading lung who were treated in our hospital from February 2020 to February 2021 were selected as the research subjects,and were divided into the control group and the observation group according to the random number table method,with 46 cases in each group.The control group was given oral loratadine syrup,and the observation group was given dispelling pathogenic wind,dispersing lung qi and strengthening spleen therapy on the basis of the treatment of the control group.Results:The obvious effective rate of treatment in the observation group was 95.65%(44/46),which was higher than 82.61%(38/46)in the control group(P<0.05).After treatment,the cough symptom score of patients in the observation group was lower than that of the control group(P<0.05),and the cough relief time,cough disappearance time,and lung rales disappearance time were shorter than those in the control group(P<0.05).After treatment,the levels of serum interleukin-4(IL-4),tumor necrosis factor-α(TNF-α),interleukin-5(IL-5)and interleukin-6(IL-6)of patients in the observation group were lower than those of the control group(P<0.05).Conclusion:The method of dispelling pathogenic wind,dispersing lung qi and strengthening spleen therapy combined with oral loratadine syrup to treat atopic cough children with the syndrome of wind evil invading lung is beneficial to improve the treatment effect and relieve the cough symptoms of patients,and is beneficial to shorten the clinical recovery time and reduce the level of inflammatory factors.
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