MSCT、SPECT对脑白质疏松症的诊断价值及其全脑保护治疗前后血流动力学分析  

Analysis on MSCT and SPECT for Leukoaraiosis and the Changes of Hemodynamics before and after whole Brain Protective Treatment

作　　者：高建强 王娟 GAO Jian-qiang;WANG Juan(Department of Nuclear Medicine,Shanghai Jingan District Zhabei Central Hospital,Shanghai 200070,China)

机构地区：[1]上海市静安区闸北中心医院核医学科,上海200070

出　　处：《中国CT和MRI杂志》2022年第5期49-50,60,共3页Chinese Journal of CT and MRI

基　　金：上海市自然科学基金(16ZR1433400)。

摘　　要：目的 分析多层螺旋CT(MSCT)、单光子发射计算机断层扫描(SPECT)对脑白质疏松症的诊断价值及其全脑保护治疗前后血流动力学变化情况。方法 回顾性分析2017年3月至2019年6月收治的68例脑白质疏松症患者的临床资料,将MSCT检查和SPECT检查的诊断结果进行讨论和分析,比较两种检查不同解剖部位的阳性率情况,观察脑白质疏松症患者全脑保护治疗前后基底动脉(BA)及双侧椎动脉(VA),双侧大脑前、中、后动脉(ACA、MCA、PCA)的血流平均速度(Vm)改变。结果 SPECT检查发现脑白质疏松症患者灰质rCBF减少者为69.12%,白质rCBF减少者为32.88%,MSCT检查发现脑白质疏松症患者灰质rCBF减少者为11.76%,白质rCBF减少者为100%;治疗前的MCA、ACA、PCA、BA、VA的Vm显著低于治疗后(P<0.05)。结论 MSCT检查和SPECT检查可清楚显示脑白质疏松症的影像学特点,根据影像学提供的资料对脑白质疏松症患者进行全脑保护治疗,可明显改善患者临床症状,减少致残率。Objective To analyze the diagnostic value of multi-slice spiral CT(MSCT) and single photon emission computed tomography(SPECT) for leukoaraiosis and the changes of hemodynamics before and after whole brain protective treatment. Methods The clinical data of 68 patients with leukoaraiosis who were admitted from March 2017 to June 2019 were retrospectively analyzed. The diagnosis results of MSCT and SPECT were discussed and analyzed. To compare the positive rates of the two examinations on different anatomical sites, and to observe the changes of mean velocity of blood flow(Vm) in the basilar artery(BA) and bilateral vertebral artery(VA) and bilateral anterior, middle and posterior cerebral arteries(ACA, MCA, PCA) of patients with leukoaraiosis before and after the whole brain protective treatment. Results SPECT examination found that the proportion of patients with decreasing of gray matter rCBF in patients with leukoaraiosis was 69.12%, the proportion of patients with decreasing of white matter rCBF in patients with leukoaraiosis was 32.88%. MSCT showed that the proportion of patients with decreasing of gray matter rCBF in patients with leukoaraiosis was 11.76%, the proportion of patients with decreasing of white matter rCBF in patients with leukoaraiosis was 100%. The Vm of MCA, ACA, PCA, BA, and VA before treatment was significantly lower than that after treatment(P<0.05). Conclusion MSCT examination and SPECT examination can clearly show the imaging characteristics of leukoaraiosis. According to the information provided by imaging, whole brain protective treatment for patients with leukoaraiosis can significantly improve the clinical symptoms and reduce the disability rate.

关 键 词：多层螺旋CT 计算机断层扫描 全脑 保护治疗 

分 类 号：R445.3[医药卫生—影像医学与核医学]